Molecular structure of Octopamine Hydrochloride, CAS Number: 770-05-8
Octopamine Hydrochloride (CAS 770-05-8)
Alternate Names:
Epirenor; Norden; Norfen; Norphen
Application:
Octopamine Hydrochloride is an activator of β3-AR and α2A-AR adrenoceptors
CAS Number:
770-05-8
Purity:
≥97%
Molecular Weight:
189.64
Molecular Formula:
C8H11NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Octopamine hydrochloride is an invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor (AR) agonist. Octopamine hydrochloride stimulates lipolysis in mammalian adipocytes via activation of beta3-AR receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via beta3-AR receptor activation but stimulates transport when oxidised by MAO. Also activates human alpha2A-AR receptors, inhibiting subsequent cAMP production.
Octopamine Hydrochloride (CAS 770-05-8) References
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- Rapid freeze- and chemical-quench studies of dopamine beta-monooxygenase: comparison of pre-steady-state and steady-state parameters. | Brenner, MC., et al. 1989. Biochemistry. 28: 4656-64. PMID: 2548586
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- Comparative antiradical activity and molecular Docking/Dynamics analysis of octopamine and norepinephrine: the role of OH groups. | Dimić, D., et al. 2020. Comput Biol Chem. 84: 107170. PMID: 31810852
- Serum octopamine, coma, and charcoal haemoperfusion in fulminant hepatic failure. | Chase, RA., et al. 1977. Eur J Clin Invest. 7: 351-4. PMID: 411665
- Plasma dopamine- -hydroxylase activity in hypertension and various neuropsychiatric disorders. | Wetterberg, L., et al. 1972. Scand J Clin Lab Invest. 30: 283-9. PMID: 4264461
- Tissue distribution of exogenously administered, and endogenously accumulated octopamine in rats. | Osumi, S. and Fujiwara, M. 1969. Jpn J Pharmacol. 19: 185-93. PMID: 4905655
- Rapid estimation of catecholamines, octopamine and 5-hydroxytryptamine in biological tissues using high-performance liquid chromatography with coulometric detection. | Martin, RJ., et al. 1983. J Chromatogr. 278: 265-74. PMID: 6421859
- Selective inhibition of adenylyl cyclase by octopamine via a human cloned alpha 2A-adrenoceptor. | Airriess, CN., et al. 1997. Br J Pharmacol. 122: 191-8. PMID: 9313925
Activator of:
alpha2A-AR, and beta3-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Octopamine Hydrochloride, 1 g | sc-203168 | 1 g | $51.00 | |||
Octopamine Hydrochloride, 5 g | sc-203168A | 5 g | $87.00 |