Date published: 2026-4-24

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Octenidine Dihydrochloride (CAS 70775-75-6)

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Alternate Names:
N,N′-[Decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene]bis(octylammonium) dichloride
CAS Number:
70775-75-6
Molecular Weight:
623.83
Molecular Formula:
C36H64Cl2N4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Octenidine hydrochloride, an active ingredient prominently utilized in numerous antiseptic, antibacterial, and antifungal products, holds significant importance. This quaternary ammonium compound serves as the salt derived from octenidine and hydrochloric acid. Widely recognized for its exceptional antiseptic and antifungal properties, octenidine hydrochloride finds extensive application in medical, industrial, and even food and cosmetic realms. In-depth research into octenidine hydrochloride has shed light on its remarkable biochemical and physiological effects. Its efficacy in eradicating bacteria, fungi, and certain viruses has been demonstrated conclusively. Acting as an antiseptic, octenidine hydrochloride disrupts the microorganism′s cell membrane, impairs vital metabolic pathways, and interferes with essential protein synthesis. Furthermore, it exhibits potent fungicidal activity and hampers the formation of biofilms. Within the domain of scientific investigation, octenidine hydrochloride has been subject to extensive studies. Its efficacy in treating bacterial and fungal infections has been explored in vitro, showcasing its effectiveness against both gram-positive and gram-negative bacteria. Moreover, researchers have evaluated its potential as a combatant against viruses, revealing its favorable outcomes in combating select viral strains. The versatile nature and proven efficacy of octenidine hydrochloride have propelled its widespread utilization. As a key component in various antiseptic, antibacterial, and antifungal formulations, it continues to pave the way for innovative applications and promising advancements in multiple fields.


Octenidine Dihydrochloride (CAS 70775-75-6) References

  1. Effect of octenidine dihydrochloride on viability of protoscoleces in hepatic and pulmonary hydatid diseases.  |  Ciftci, IH., et al. 2007. J Natl Med Assoc. 99: 674-7. PMID: 17595938
  2. The percutaneous permeation of a combination of 0.1% octenidine dihydrochloride and 2% 2-phenoxyethanol (octenisept®) through skin of different species in vitro.  |  Stahl, J., et al. 2011. BMC Vet Res. 7: 44. PMID: 21835019
  3. Antibacterial Effects and Biocompatibility of Titania Nanotubes with Octenidine Dihydrochloride/Poly(lactic-co-glycolic acid).  |  Xu, Z., et al. 2015. Biomed Res Int. 2015: 836939. PMID: 26090449
  4. In vitro effect of octenidine dihydrochloride against Trichomonas vaginalis.  |  Küng, E., et al. 2016. Int J Antimicrob Agents. 47: 232-4. PMID: 26899578
  5. New lipid formulation of octenidine dihydrochloride.  |  Szostak, K., et al. 2018. J Liposome Res. 28: 106-111. PMID: 28006995
  6. Consensus on Wound Antisepsis: Update 2018.  |  Kramer, A., et al. 2018. Skin Pharmacol Physiol. 31: 28-58. PMID: 29262416
  7. Antifungal activity of octenidine dihydrochloride and ultraviolet-C light against multidrug-resistant Candida auris.  |  Ponnachan, P., et al. 2019. J Hosp Infect. 102: 120-124. PMID: 30261239
  8. The Antibacterial Activity of Lavender Essential Oil Alone and In Combination with Octenidine Dihydrochloride against MRSA Strains.  |  Kwiatkowski, P., et al. 2019. Molecules. 25: PMID: 31888005
  9. Octenidine/carbenicillin GUMBOS as potential treatment for oropharyngeal gonorrhoea.  |  Lopez, KM., et al. 2020. J Antimicrob Chemother. 75: 3576-3581. PMID: 32830243
  10. Iso-octenidine: Promising Octenidine Analogue with Improved Solubility.  |  Yakuschenko, IK., et al. 2021. Curr Org Synth. 18: 443-445. PMID: 33390116
  11. Octenidine-based hydrogel shows anti-inflammatory and protease-inhibitory capacities in wounded human skin.  |  Seiser, S., et al. 2021. Sci Rep. 11: 32. PMID: 33420112
  12. Octenidine dihydrochloride treatment of a meticillin-resistant Staphylococcus aureus biofilm-infected mouse wound.  |  Huang, J., et al. 2021. J Wound Care. 30: 106-114. PMID: 33573482
  13. [Evaluation of effectiveness of a mouthwash containing antiseptic octenidine dihydrochloride].  |  Sabanceva, EG., et al. 2021. Stomatologiia (Mosk). 100: 32-39. PMID: 33874658
  14. The cross-linked bacterial cellulose impregnated with octenidine dihydrochloride-based antiseptic as an antibacterial dressing material for highly-exuding, infected wounds.  |  Ciecholewska-Juśko, D., et al. 2022. Microbiol Res. 263: 127125. PMID: 35878492
  15. Improved efficacy of eugenol and trans-anethole in combination with octenidine dihydrochloride against Candida albicans and Candida parapsilosis.  |  Dąbrowska, M., et al. 2023. Ann Agric Environ Med. 30: 204-210. PMID: 36999876

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Octenidine Dihydrochloride, 1 g

sc-478739
1 g
$263.00