Octanoyl coenzyme A lithium salt (CAS 324518-20-9)
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Octanoyl coenzyme A lithium salt hydrate is a chemically modified form of octanoyl-CoA, a medium-chain acyl-CoA derivative involved in numerous metabolic processes, particularly in the metabolism of fatty acids. The lithium salt form and its hydration status enhance its stability and solubility, making it useful for various biochemical applications and studies. The lithium ion associates with the negatively charged phosphate groups of the CoA, stabilizing the overall structure. Octanoyl coenzyme A lithium salt hydrate is used in studies focusing on enzymes involved in fatty acid metabolism, such as acyl-CoA dehydrogenase, which catalyzes the first step of the beta-oxidation cycle. It serves as a substrate or inhibitor in assays designed to dissect various metabolic pathways, providing insights into the regulation and efficiency of fatty acid utilization and energy production.
Octanoyl coenzyme A lithium salt (CAS 324518-20-9) References
- Benzoyl-CoA conjugate accumulation as an initiating event for male reprotoxic effects in the rat? Structure-activity analysis, species specificity, and in vivo relevance. | Laue, H., et al. 2020. Arch Toxicol. 94: 4115-4129. PMID: 33057782
- CROT (Carnitine O-Octanoyltransferase) Is a Novel Contributing Factor in Vascular Calcification via Promoting Fatty Acid Metabolism and Mitochondrial Dysfunction. | Okui, T., et al. 2021. Arterioscler Thromb Vasc Biol. 41: 755-768. PMID: 33356393
- Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection. | Beites, T., et al. 2021. Nat Commun. 12: 6593. PMID: 34782606
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Octanoyl coenzyme A lithium salt, 5 mg | sc-215619 | 5 mg | $231.00 | |||
Octanoyl coenzyme A lithium salt, 10 mg | sc-215619A | 10 mg | $401.00 | |||
Octanoyl coenzyme A lithium salt, 25 mg | sc-215619B | 25 mg | $811.00 |