Date published: 2026-4-25

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Octadecenylsuccinic Anhydride (CAS 28777-98-2)

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CAS Number:
28777-98-2
Molecular Weight:
350.54
Molecular Formula:
C22H38O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Octadecenylsuccinic anhydride serves as a reactive intermediate in organic synthesis, utilized for its acylating capabilities. It effectively establishes covalent linkages with nucleophilic entities such as amines and alcohols. This reactivity is facilitated through the nucleophilic attack on the anhydride′s carbonyl groups, culminating in the formation of robust amide or ester bonds. Octadecenylsuccinic anhydride utility extends to the modification of surface characteristics of various substrates, including polymers and nanoparticles. By covalently attaching to these materials, octadecenylsuccinic anhydride significantly alters their physical and chemical attributes, thereby enhancing their functionality in diverse applications. This attribute makes it important in the synthesis and development of novel materials, enabling to engineer products with specific, desirable properties tailored to meet the demands of advanced technological applications.


Octadecenylsuccinic Anhydride (CAS 28777-98-2) References

  1. Adsorption of hydrophobically end-capped poly(ethylene glycol) on cellulose.  |  Holappa, S., et al. 2013. Langmuir. 29: 13750-9. PMID: 24117230
  2. Stabilizing alkenyl succinic anhydride (ASA) emulsions with starch nanocrystals and fluorescent carbon dots.  |  Gong, B., et al. 2017. Carbohydr Polym. 165: 13-21. PMID: 28363532
  3. Modulation of Cyclodextrin Particle Amphiphilic Properties to Stabilize Pickering Emulsion.  |  Xi, Y., et al. 2018. J Agric Food Chem. 66: 228-237. PMID: 29251505
  4. pH-Responsive Emulsions with β-Cyclodextrin/Vitamin E Assembled Shells for Controlled Delivery of Polyunsaturated Fatty Acids.  |  Xi, Y., et al. 2019. J Agric Food Chem. 67: 11931-11941. PMID: 31589419
  5. Preparation of water-repellent silks by a reaction with octadecenylsuccinic anhydride  |  Takayuki Arai, Giuliano Freddi, Riccardo Innocenti, Masuhiro Tsukada. 2003. Journal of Applied Polymer Science. 89: 324-332.
  6. Use of Acrylic Functionalized (Meth)acrylic Cross-Linked Polymer Microparticles in Photopolymerized Acrylic Films  |  Ludovic Valette, Jean-Pierre Pascault, Benoît Magny. 2003. Macromolecular Materials and Engineering. 288: 642-657.
  7. Process optimization for the synthesis of octenyl succinyl derivative of waxy corn and amaranth starches  |  Rajesh Bhosale, Rekha Singhal. 2006. Carbohydrate Polymers. 66: 521-527.
  8. Reactions between cellulose diacetate and alkenylsuccinic anhydrides and characterization of the reaction products  |  Tsuyoshi Takihara, Yutaka Yoshida & Akira Isogai. 2007. Cellulose. 14: 357–366.
  9. Optimization of starch oleate derivatives from native corn and hydrolyzed corn starch by response surface methodology  |  Amol C. Kshirsagar, Rekha S. Singhal. 2007. Carbohydrate Polymers. 69: 455-461.
  10. Octadecenylsuccinic anhydride pickering emulsion stabilized by γ-methacryloxy propyl trimethoxysilane grafted montmorillonite  |  Dehai Yu, Zhaoyun Lin, Youming Li. 2013. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 422: 100-109.
  11. Preparation and evaluation of hydrophobically modified core shell calcium carbonate structure by different capping agents  |  Deepika a b, S.K. Hait a, J. Christopher a, Y. Chen b, P. Hodgson b, D.K. Tuli a. 2013. Powder Technology. 235: 581-589.
  12. Behavior of Cellulose Reinforced Cross-Linked Starch Composite Films Made with Tartaric Acid Modified Starch Microparticles  |  Iuliana Spiridon, Carmen-Alice Teacă, Ruxanda Bodîrlău & Maria Bercea. 2013. Journal of Polymers and the Environment. 21: 431–440.
  13. Miscibility and flexibility of poly(lactic acid) blends with octadecenylsuccinic anhydride  |  Trong-Ming Don, Ting-Shu Li, Wei-Chi Lai. 2019. Polymer Degradation and Stability. 162: 55-65.
  14. High internal phase pickering emulsions stabilized by ODSA-functionalized cyclodextrin metal-organic frameworks for extrusion 3D printing application  |  Yannan Zhang a, Dehai Yu. 2023. LWT. 182.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Octadecenylsuccinic Anhydride, 25 g

sc-488226
25 g
$59.00