Molecular structure of Ochratoxin B, CAS Number: 4825-86-9
Ochratoxin B (CAS 4825-86-9)
See product citations (12)
Application:
Ochratoxin B is the non-chlorinated and less potent analog of Ochratoxin A
CAS Number:
4825-86-9
Purity:
>99%
Molecular Weight:
369.4
Molecular Formula:
C20H19NO6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ochratoxin B, a dihydroisocoumarin derivative, is the non-chlorinated analogue of the much more extensively studied Ochratoxin A (sc-202749). The compound is coproduced by the same species of Aspergillus and Penicillium that are associated with food spoilage. When Ochratoxin B was administered in rats the presence of two fluorescent metabolites, 4-hydroxyochratoxin B and ochratoxin β were found in the urine. Ochratoxin B has been shown to induce facial abnormalities when applied to the Xenopus embryo. The compound has not displayed genotoxic activity in human derived cells. Ochratoxin B has been shown to reduce the toxic effects caused by Ochratoxin A.
Ochratoxin B (CAS 4825-86-9) References
- Structurally related mycotoxins ochratoxin A, ochratoxin B, and citrinin differ in their genotoxic activities and in their mode of action in human-derived liver (HepG2) cells: implications for risk assessment. | Knasmüller, S., et al. 2004. Nutr Cancer. 50: 190-7. PMID: 15623466
- Investigation of the teratogenic potential of ochratoxin A and B using the FETAX system. | O'Brien, E., et al. 2005. Birth Defects Res B Dev Reprod Toxicol. 74: 417-23. PMID: 16167345
- Toxico-pathological effects of ochratoxin A and its diastereoisomer under in ovo conditions and in vitro evaluation of the toxicity of these toxins against the embryo Gallus gallus fibroblast cell line. | Bryła, M., et al. 2023. Poult Sci. 102: 102413. PMID: 36566659
- First genome-scale insights into the virulence of the snow mold causal fungus Microdochium nivale. | Tsers, I., et al. 2023. IMA Fungus. 14: 2. PMID: 36627722
- Purification and characterization of the enzymes from Brevundimonas naejangsanensis that degrade ochratoxin A and B. | Peng, M., et al. 2023. Food Chem. 419: 135926. PMID: 37011575
- An Extremely Highly Sensitive ELISA in pg mL-1 Level Based on a Newly Produced Monoclonal Antibody for the Detection of Ochratoxin A in Food Samples. | Ren, Y., et al. 2023. Molecules. 28: PMID: 37570711
- Histone Deacetylase UvHST2 Is a Global Regulator of Secondary Metabolism in Ustilaginoidea virens. | Liu, L., et al. 2023. J Agric Food Chem. 71: 13124-13136. PMID: 37615365
- Degradation of ochratoxins A and B by lipases: A kinetic study unraveled by molecular modeling. | Santos, J., et al. 2023. Heliyon. 9: e19921. PMID: 37809625
- Associated factors with mycotoxin exposure in Spanish population. | Dasí-Navarro, N., et al. 2024. Environ Res. 242: 117618. PMID: 37967699
- Dietary Exposure and Risk Assessment of Multi-Mycotoxins (AFB1, AFM1, OTA, OTB, DON, T-2 and HT-2) in the Lebanese Food Basket Consumed by Adults: Findings from the Updated Lebanese National Consumption Survey through a Total Diet Study Approach. | Hoteit, M., et al. 2024. Toxins (Basel). 16: PMID: 38535824
- Analysis of Mycotoxins and Cytotoxicity of Airborne Molds Isolated from the Zoological Garden-Screening Research. | Plewa-Tutaj, K., et al. 2024. Pathogens. 13: PMID: 38668249
- Metabolism of ochratoxin B and its possible effects upon the metabolism and toxicity of ochratoxin A in rats. | Størmer, FC., et al. 1985. Appl Environ Microbiol. 49: 1108-12. PMID: 4004232
- Mycotoxins. II. The constitution of ochratoxins A, B, and C, metabolites of Aspergillus ochraceus Wilh. | Van der Merwe, KJ., et al. 1965. J Chem Soc Perkin 1. 7083-8. PMID: 5892024
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ochratoxin B, 1 mg | sc-202258 | 1 mg | $334.00 | |||
Ochratoxin B, 5 mg | sc-202258A | 5 mg | $739.00 |