Molecular structure of O-Succinyl-L-homoserine, CAS Number: 1492-23-5
O-Succinyl-L-homoserine (CAS 1492-23-5)
Alternate Names:
2-amino-4-((3-carboxypropanoyl)oxy)butanoic acid
Application:
O-Succinyl-L-homoserine is a homoserine derivative with a succinic ester side chain
CAS Number:
1492-23-5
Molecular Weight:
219.19
Molecular Formula:
C8H13NO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
O-Succinyl-L-homoserine is a homoserine derivative with a succinic ester side chain. O-succinyl-L-homoserine is a derivative of L-homoserine that carries an O-succinyl group. This compound serves as a metabolite in both Saccharomyces cerevisiae and Escherichia coli. It can be classified as a hemisuccinate and o-succinylhomoserine. Furthermore, it acts as the conjugate acid of O-succinyl-L-homoserinate(1-).
O-Succinyl-L-homoserine (CAS 1492-23-5) References
- Escherichia coli cystathionine gamma-synthase does not obey ping-pong kinetics. Novel continuous assays for the elimination and substitution reactions. | Aitken, SM., et al. 2003. Biochemistry. 42: 11297-306. PMID: 14503880
- Exploration of the active site of Escherichia coli cystathionine γ-synthase. | Jaworski, AF., et al. 2012. Protein Sci. 21: 1662-71. PMID: 22855027
- Purification and properties of cystathionine gamma-synthase from overproducing strains of Escherichia coli. | Holbrook, EL., et al. 1990. Biochemistry. 29: 435-42. PMID: 2405903
- Reaction mechanism of Escherichia coli cystathionine gamma-synthase: direct evidence for a pyridoxamine derivative of vinylglyoxylate as a key intermediate in pyridoxal phosphate dependent gamma-elimination and gamma-replacement reactions. | Brzović, P., et al. 1990. Biochemistry. 29: 442-51. PMID: 2405904
- Modified Jiu Wei Qiang Huo decoction improves dysfunctional metabolomics in influenza A pneumonia-infected mice. | Chen, L., et al. 2014. Biomed Chromatogr. 28: 468-74. PMID: 24132661
- O-Succinyl-L-homoserine-based C4-chemical production: succinic acid, homoserine lactone, γ-butyrolactone, γ-butyrolactone derivatives, and 1,4-butanediol. | Hong, KK., et al. 2014. J Ind Microbiol Biotechnol. 41: 1517-24. PMID: 25155257
- Structural Insights into Substrate Specificity of Cystathionine γ-Synthase from Corynebacterium glutamicum. | Sagong, HY. and Kim, KJ. 2017. J Agric Food Chem. 65: 6002-6008. PMID: 28675039
- Metabolic engineering of E. coli for the production of O-succinyl-l-homoserine with high yield. | Huang, JF., et al. 2018. 3 Biotech. 8: 310. PMID: 30002999
- Enhanced production of L-methionine in engineered Escherichia coli with efficient supply of one carbon unit. | Tang, XL., et al. 2020. Biotechnol Lett. 42: 429-436. PMID: 31865476
- Underground isoleucine biosynthesis pathways in E. coli. | Cotton, CA., et al. 2020. Elife. 9: PMID: 32831171
- Enhanced O-succinyl-l-homoserine production by recombinant Escherichia coli ΔIJBB*TrcmetL/pTrc-metAfbr -Trc-thrAfbr -yjeH via multilevel fermentation optimization. | Zhu, WY., et al. 2021. J Appl Microbiol. 130: 1960-1971. PMID: 33025634
- O-Succinyl-l-homoserine overproduction with enhancement of the precursor succinyl-CoA supply by engineered Escherichia coli. | Liu, P., et al. 2021. J Biotechnol. 325: 164-172. PMID: 33157196
- Identification and Characterization of an O-Succinyl-L-Homoserine Sulfhydrylase From Thioalkalivibrio sulfidiphilus. | Zhu, WY., et al. 2021. Front Chem. 9: 672414. PMID: 33937207
- Combining fermentation to produce O-succinyl-l-homoserine and enzyme catalysis for the synthesis of l-methionine in one pot. | Zhu, WY., et al. 2021. J Biosci Bioeng. 132: 451-459. PMID: 34420895
- [Advances in the biosynthesis of L-homoserine and its derivatives by metabolic engineering of Escherichia coli]. | Niu, K., et al. 2022. Sheng Wu Gong Cheng Xue Bao. 38: 4385-4402. PMID: 36593184
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
O-Succinyl-L-homoserine, 25 mg | sc-215613 | 25 mg | $104.00 | |||
O-Succinyl-L-homoserine, 100 mg | sc-215613A | 100 mg | $322.00 |