o-Phthalaldehyde-d6 (CAS 68234-47-9)

o-Phthalaldehyde-d6 is a deuterium-labeled analog of o-phthalaldehyde, often abbreviated as OPA-d6, where six hydrogen atoms have been replaced by deuterium. This compound is widely used in analytical chemistry, particularly in the field of liquid chromatography and mass spectrometry (LC-MS), as an internal standard to improve the accuracy of quantitative analyses. In the context of research involving aldehydes and their reactivity, OPA-d6′s increased mass due to the presence of deuterium allows for differentiation from the non-labeled species, facilitating studies on reaction kinetics and mechanisms. Additionally, its application in derivatization reactions of amines forms highly fluorescent products, enabling sensitive detection of these compounds in complex mixtures. The use of o-Phthalaldehyde-d6 in environmental and biochemical studies helps to trace the transformation and degradation pathways of phthalaldehyde-related substances, contributing to a deeper understanding of their behavior in various systems.