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O-Methyl-L-threonine (CAS 4144-02-9)

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Alternate Names:
L-Thr(Me)-OH; (S)-2-Amino-3-methoxybutanoic acid
CAS Number:
4144-02-9
Purity:
≥99%
Molecular Weight:
133.15
Molecular Formula:
C5H11NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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O-Methyl-L-threonine is a derivative of L-threonine, possessing similar structural characteristics. This compound has been found to effectively suppress the synthesis of fatty acids in resistant mutants, particularly by modifying the amino acid backbone with the addition of a hydroxy group. Additionally, O-Methyl-L-threonine serves as a precursor for the synthesis of nicotinic acetylcholine. It can also be used as photoresists.


O-Methyl-L-threonine (CAS 4144-02-9) References

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  2. Interaction between the synthesis of alpha and beta globin.  |  Garrick, LM., et al. 1975. Eur J Biochem. 58: 339-50. PMID: 1183442
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  7. Regio- and Enantioselective Synthesis of Trifluoromethyl-Substituted Homoallylic α-Tertiary NH2 -Amines by Reactions Facilitated by a Threonine-Based Boron-Containing Catalyst.  |  Fager, DC., et al. 2020. Angew Chem Int Ed Engl. 59: 11448-11455. PMID: 32219997
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  10. Dipeptides of O-methyl-L-threonine as potential antimalarials.  |  Gershon, H. and Krull, IS. 1979. J Med Chem. 22: 877-9. PMID: 376849
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  13. Enzymes of the isoleucine-valine pathway in Acinetobacter.  |  Twarog, R. 1972. J Bacteriol. 111: 37-46. PMID: 4669215

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

O-Methyl-L-threonine, 250 mg

sc-295956
250 mg
$112.00

O-Methyl-L-threonine, 1 g

sc-295956A
1 g
$199.00