O-Desmethyl galanthamine (CAS 60755-80-8)
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O-Desmethyl Galanthamine is a compound that functions as an acetylcholinesterase inhibitor. It acts by binding to the active site of the enzyme, preventing the hydrolysis of acetylcholine. This inhibition leads to an increase in the concentration of acetylcholine in the synaptic cleft, enhancing cholinergic neurotransmission. At the molecular level, O-Desmethyl Galanthamine forms hydrogen bonds and hydrophobic interactions with specific amino acid residues in the active site of acetylcholinesterase, thereby disrupting its catalytic function. It plays a role in modulating cholinergic signaling pathways. Its mechanism of action provides insights into the regulation of neurotransmission and synaptic plasticity, contributing to the understanding of neuronal communication.
O-Desmethyl galanthamine (CAS 60755-80-8) References
- High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of galantamine and its phase I metabolites in biological samples. | Maláková, J., et al. 2007. J Chromatogr B Analyt Technol Biomed Life Sci. 853: 265-74. PMID: 17416214
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
O-Desmethyl galanthamine, 5 mg | sc-208117 | 5 mg | $296.00 |