O-Acetyl Scopolamine Hydrobromide (CAS 5027-67-8)

O-Acetyl Scopolamine Hydrobromide, a quaternary ammonium derivative of scopolamine, exhibits a distinctive mode of action primarily through its interaction with the muscarinic acetylcholine receptors (mAChRs). This compound, being a more stable and lipid-soluble form of scopolamine, can effectively cross cellular membranes, thereby enhancing its research applicability, especially in studies involving the peripheral nervous system. Its hydrobromide salt form increases its solubility, making it particularly useful in various experimental setups. In research applications, O-Acetyl Scopolamine Hydrobromide is pivotal in elucidating the physiological and pathological roles of cholinergic signaling pathways. By selectively modulating mAChRs, it aids in dissecting the intricate mechanisms underlying neurotransmission and its impact on various cellular processes. This chemical entity serves as a powerful tool in neuropharmacological research, facilitating the exploration of cholinergic system functions, including memory, learning, and neuronal plasticity. Its application extends to investigating the molecular basis of disorders characterized by dysregulated acetylcholine signaling, thereby contributing to the broader understanding of nervous system dynamics.