Molecular structure of O-Acetyl-L-homoserine Hydrochloride, CAS Number: 250736-84-6
O-Acetyl-L-homoserine Hydrochloride (CAS 250736-84-6)
Alternate Names:
L-Homoserine Acetate Hydrochloride
Application:
O-Acetyl-L-homoserine Hydrochloride is a versatile synthon used for the synthesis of L-Homoserine peptides
CAS Number:
250736-84-6
Purity:
≥95%
Molecular Weight:
197.62
Molecular Formula:
C6H11NO4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
O-Acetyl-L-homoserine Hydrochloride (OAH) is a versatile synthon used for the synthesis of L-Homoserine peptides and 3-Amino-2-pyrrolidinones. It is also an inhibitor of enzymes as well as a substrate for enzymes. O-Acetyl-L-homoserine Hydrochloride is used in a variety of scientific research applications, including enzyme reactions, protein synthesis, DNA sequencing, and drug discovery. It has been reported to inhibit the growth of certain bacteria and has been used to study the effects of drugs on the nervous system. Additionally, it can affect the metabolism of certain hormones.
O-Acetyl-L-homoserine Hydrochloride (CAS 250736-84-6) References
- Role of tyrosine 114 of L-methionine gamma-lyase from Pseudomonas putida. | Inoue, H., et al. 2000. Biosci Biotechnol Biochem. 64: 2336-43. PMID: 11193400
- Occurrence of transsulfuration in synthesis of L-homocysteine in an extremely thermophilic bacterium, Thermus thermophilus HB8. | Yamagata, S., et al. 2001. J Bacteriol. 183: 2086-92. PMID: 11222609
- Antisense repression of the Medicago truncatula nodule-enhanced sucrose synthase leads to a handicapped nitrogen fixation mirrored by specific alterations in the symbiotic transcriptome and metabolome. | Baier, MC., et al. 2007. Plant Physiol. 145: 1600-18. PMID: 17951459
- Development of bottom-fermenting saccharomyces strains that produce high SO2 levels, using integrated metabolome and transcriptome analysis. | Yoshida, S., et al. 2008. Appl Environ Microbiol. 74: 2787-96. PMID: 18310411
- In vitro incorporation of selenium into tRNAs of Salmonella typhimurium. | Veres, Z., et al. 1990. Proc Natl Acad Sci U S A. 87: 6341-4. PMID: 2117280
- Coupling bioorthogonal chemistries with artificial metabolism: intracellular biosynthesis of azidohomoalanine and its incorporation into recombinant proteins. | Ma, Y., et al. 2014. Molecules. 19: 1004-22. PMID: 24434673
- Structural Insights into Substrate Specificity of Cystathionine γ-Synthase from Corynebacterium glutamicum. | Sagong, HY. and Kim, KJ. 2017. J Agric Food Chem. 65: 6002-6008. PMID: 28675039
- Self-Directed in Cell Production of Methionine Analogue Azidohomoalanine by Synthetic Metabolism and Its Incorporation into Model Proteins. | Ma, Y., et al. 2018. Methods Mol Biol. 1728: 127-135. PMID: 29404994
- The Complete Pathway for Thiosulfate Utilization in Saccharomyces cerevisiae. | Chen, Z., et al. 2018. Appl Environ Microbiol. 84: PMID: 30217845
- Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site. | Chaton, CT., et al. 2019. Sci Rep. 9: 20267. PMID: 31889085
- Discovery and Biocatalytic Application of a PLP-Dependent Amino Acid γ-Substitution Enzyme That Catalyzes C-C Bond Formation. | Chen, M., et al. 2020. J Am Chem Soc. 142: 10506-10515. PMID: 32434326
- Partial purification and some properties of homoserine O-acetyltransferase of a methionine auxotroph of Saccharomyces cerevisiae. | Yamagata, S. 1987. J Bacteriol. 169: 3458-63. PMID: 3301801
- O-Acetyl-L-homoserine production enhanced by pathway strengthening and acetate supplementation in Corynebacterium glutamicum. | Li, N., et al. 2022. Biotechnol Biofuels Bioprod. 15: 27. PMID: 35287716
- Purification and characterization of cystathionine gamma-synthase type II from Bacillus sphaericus. | Kanzaki, H., et al. 1987. Eur J Biochem. 163: 105-12. PMID: 3816790
- O-Acetylhomoserine sulfhydrylase of the fission yeast Schizosaccharomyces pombe: partial purification, characterization, and its probable role in homocysteine biosynthesis. | Yamagata, S. 1984. J Biochem. 96: 1511-23. PMID: 6526818
- Methionine biosynthesis in Brevibacterium flavum: properties and essential role of O-acetylhomoserine sulfhydrylase. | Ozaki, H. and Shiio, I. 1982. J Biochem. 91: 1163-71. PMID: 7096282
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
O-Acetyl-L-homoserine Hydrochloride, 5 mg | sc-212443D | 5 mg | $166.00 | |||
O-Acetyl-L-homoserine Hydrochloride, 10 mg | sc-212443 | 10 mg | $364.00 | |||
O-Acetyl-L-homoserine Hydrochloride, 25 mg | sc-212443A | 25 mg | $650.00 | |||
O-Acetyl-L-homoserine Hydrochloride, 50 mg | sc-212443B | 50 mg | $1196.00 | |||
O-Acetyl-L-homoserine Hydrochloride, 100 mg | sc-212443C | 100 mg | $2091.00 |