O-(2-Nitrobenzyl)-L-tyrosine Hydrochloride (CAS 207727-86-4)
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O-(2-Nitrobenzyl)-L-tyrosine Hydrochloride is used in the synthesis of caged peptides. In peptide synthesis, it serves as a building block that can be selectively deprotected under light exposure, enabling the stepwise construction of complex peptide chains. This methodology supports the creation of peptides with precise structural and functional characteristics, facilitating research into protein structure-function relationships and the development of bioactive peptides. When exposed to light in the range of 300-350 nm it undergoes rapid photolysis resulting in the release of tyrosine. This feature is especially useful in the development of photoresponsive materials and in the study of biological systems where spatial and temporal control of molecule release is crucial.
O-(2-Nitrobenzyl)-L-tyrosine Hydrochloride (CAS 207727-86-4) References
- Rapid and Inexpensive Evaluation of Nonstandard Amino Acid Incorporation in Escherichia coli. | Monk, JW., et al. 2017. ACS Synth Biol. 6: 45-54. PMID: 27648665
- Efficient Unnatural Protein Production by Pyrrolysyl-tRNA Synthetase With Genetically Fused Solubility Tags. | Koch, NG., et al. 2021. Front Bioeng Biotechnol. 9: 807438. PMID: 35284428
- Spatiotemporal Control of Melanin Synthesis in Liquid Droplets. | Massarano, T., et al. 2022. ACS Appl Mater Interfaces. 14: 20520-20527. PMID: 35451309
- Crystal Structure of an Archaeal Tyrosyl-tRNA Synthetase Bound to Photocaged L-Tyrosine and Its Potential Application to Time-Resolved X-ray Crystallography. | Hosaka, T., et al. 2022. Int J Mol Sci. 23: PMID: 36142308
- Chemical Proteomics Reveals Protein Tyrosination Extends Beyond the Alpha-Tubulins in Human Cells. | Makarov, D. and Kielkowski, P. 2022. Chembiochem. 23: e202200414. PMID: 36218090
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
O-(2-Nitrobenzyl)-L-tyrosine Hydrochloride, 500 mg | sc-363295 | 500 mg | $204.00 | |||
O-(2-Nitrobenzyl)-L-tyrosine Hydrochloride, 1 g | sc-363295A | 1 g | $306.00 | |||
O-(2-Nitrobenzyl)-L-tyrosine Hydrochloride, 5 g | sc-363295B | 5 g | $959.00 | |||
O-(2-Nitrobenzyl)-L-tyrosine Hydrochloride, 10 g | sc-363295C | 10 g | $1533.00 | |||
O-(2-Nitrobenzyl)-L-tyrosine Hydrochloride, 25 g | sc-363295D | 25 g | $3060.00 |