NusA Antibody (1NA1): sc-101603
- NusA Antibody (1NA1) is a mouse monoclonal IgG2b provided at 100 µl ascites
- raised against NusA of E. coli origin, with epitope mapping to amino acids 343-494
- recommended for detection of NusA of E. coli, Salmonella typhimurium and Serratia marcescens origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NusA Antibody (1NA1). This work is in progress.
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NusA Antibody (1NA1) is a mouse monoclonal IgG2b antibody that detects NusA in E. coli, Salmonella typhimurium, and Serratia marcescens by western blotting (WB). NusA antibody (1NA1) is available in a non-conjugated form, providing researchers with a versatile tool for studying this essential bacterial protein. NusA plays a critical role in transcriptional regulation, particularly in transcriptional termination, and is also involved in DNA repair mechanisms. NusA interaction with the DinB polymerase is particularly noteworthy, as this relationship is vital for the bacterial response to DNA damage. The DinB polymerase, known for its error-prone nature, facilitates translesion DNA synthesis, allowing the replication machinery to bypass lesions in the DNA. This process is crucial for maintaining genomic stability, especially when replication forks encounter obstacles that could lead to breaks. Understanding NusA function and importance in these pathways provides insights into bacterial survival strategies and mechanisms underlying mutagenesis, which may have broader implications in fields such as microbiology and genetics.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NusA Antibody (1NA1) | sc-101603 | 100 µl ascites | $339.00 |