NumbL Antibody (H-5): sc-390799
- NumbL Antibody (H-5) is a mouse monoclonal mouse IgG2a κ κ provided at 200 µg/ml
- raised against amino acids 331-410 mapping within an internal region of NumbL of human origin
- recommended for detection of NumbL of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for NumbL Antibody (H-5) for WB applications. These reagents are now offered in bundles with NumbL Antibody (H-5) (see ordering information below).
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SEE ALSO...
NumbL Antibody (H-5) is a mouse monoclonal IgG2a antibody that detects NumbL in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NumbL, also known as NUMB-like protein, Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE, or TNRC23, is a 609 amino acid cytoplasmic protein that plays a crucial role in neuronal differentiation and cell fate determination during development. NumbL is expressed at high levels in developing brain tissue and contains a phosphotyrosine interaction domain, which is essential for mediating protein-protein interactions. NumbL interacts with key proteins such as Eps15 and Notch 1, which are vital for signaling pathways that influence cell fate decisions. Studies in mice show that deletion of the NumbL gene leads to early embryonic death, highlighting an essential role in early development. Anti-NumbL antibody (H-5) serves as an invaluable tool for researchers studying neuronal differentiation and related signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NumbL Antibody (H-5) | sc-390799 | 200 µg/ml | $322.00 | |||
NumbL Antibody (H-5): m-IgG Fc BP-HRP Bundle | sc-540855 | 200 µg Ab; 10 µg BP | $361.00 | |||
NumbL Antibody (H-5): m-IgG2a BP-HRP Bundle | sc-546966 | 200 µg Ab; 10 µg BP | $361.00 |