Molecular structure of Nudifloramide, CAS Number: 701-44-0
Nudifloramide (CAS 701-44-0)
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Alternate Names:
N-Methyl-2-pyridoxone-5-carboxamide; 1,6-Dihydro-1-methyl-6 -oxonicotinamide; 3-Carbamoyl-1-methyl-6-pyridone
CAS Number:
701-44-0
Purity:
≥95%
Molecular Weight:
152.15
Molecular Formula:
C7H8N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Nudifloramide is a metabolite of niacin that was first discovered in a species of nudibranch, a type of sea slug, in the year 2000. It is a small molecule that acts as an inhibitor of the enzyme acetylcholinesterase (AChE), which is responsible for the breakdown of the neurotransmitter acetylcholine (ACh). In vitro studies have demonstrated that Nudifloramide can increase the expression of genes involved in learning and memory, as well as modulate the activity of neurotransmitters such as serotonin and dopamine.
Nudifloramide (CAS 701-44-0) References
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- High-Resolution Metabolomics of 50 Neurotransmitters and Tryptophan Metabolites in Feces, Serum, and Brain Tissues Using UHPLC-ESI-Q Exactive Mass Spectrometry. | Lai, Y., et al. 2021. ACS Omega. 6: 8094-8103. PMID: 33817468
- A Method to Monitor the NAD+ Metabolome-From Mechanistic to Clinical Applications. | Giner, MP., et al. 2021. Int J Mol Sci. 22: PMID: 34638936
- Methotrexate Disposition, Anti-Folate Activity, and Metabolomic Profiling to Identify Molecular Markers of Disease Activity and Drug Response in the Collagen-Induced Arthritis Mouse Model. | Salamoun, YM., et al. 2021. Metabolites. 12: PMID: 35050146
- Bidirectional regulation role of PARP-1 in high glucose-induced endothelial injury. | Zhang, Y. and Wang, W. 2022. Exp Cell Res. 421: 113400. PMID: 36283454
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nudifloramide, 5 mg | sc-215593 | 5 mg | $379.00 |