Date published: 2026-4-5

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Nucleolar Marker Antibody (31C4): sc-57947

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Datasheets
  • Nucleolar Marker Antibody (31C4) is a mouse monoclonal IgG, cited in 1 publications, provided at 500 µl supernatant
  • raised against a nuclear preparation of S. cerevisiae origin
  • recommended for detection of Nucleolar Marker of S. cerevisiae origin by WB, IP and IF
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Nucleolar Marker Antibody (31C4). This work is in progress.
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Nucleolar Marker Antibody (31C4) is a mouse monoclonal IgG antibody that detects Nucleolar Marker of S. cerevisiae origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-Nucleolar Marker antibody (31C4) is available as the non-conjugated form. The nucleolus, a vital substructure within the nucleus, plays a crucial role in the production and assembly of ribosomal components, which are essential for protein synthesis in all living cells. This organelle is not only responsible for the maturation and trafficking of various small RNA species but also contributes to critical cellular processes such as cell cycle regulation and the modulation of tumor suppressor and oncogene activities. The nucleolus is composed of distinct regions, including fibrillar centers, dense fibrillar components, and granular components, which together facilitate the intricate processes of ribosome biogenesis. A unique structure, which lacks a surrounding membrane, allows for dynamic interactions with the nucleoplasm, making the nucleolus a key player in cellular homeostasis and response to stress. Additionally, the nucleolus is involved in the modification of small RNA strands and plays a role in aging and telomerase regulation, highlighting its importance in both normal cellular function and disease states. Nucleolar Marker (31C4) antibody is an invaluable tool for researchers investigating nucleolar dynamics and its implications in various biological contexts.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Nucleolar Marker Antibody (31C4) References:

  1. The nucleolus and transcription of ribosomal genes.  |  Raska, I., et al. 2004. Biol Cell. 96: 579-94. PMID: 15519693
  2. The nucleolus. Playing by different rules?  |  Shaw, P. and Doonan, J. 2005. Cell Cycle. 4: 102-5. PMID: 15655371
  3. The moving parts of the nucleolus.  |  Olson, MO. and Dundr, M. 2005. Histochem Cell Biol. 123: 203-16. PMID: 15742198
  4. Nucleolonema as a fundamental substructure of the nucleolus.  |  Sato, S., et al. 2005. J Plant Res. 118: 71-81. PMID: 15843864
  5. The Shwachman-Diamond SBDS protein localizes to the nucleolus.  |  Austin, KM., et al. 2005. Blood. 106: 1253-8. PMID: 15860664
  6. A wiring of the human nucleolus.  |  Hinsby, AM., et al. 2006. Mol Cell. 22: 285-95. PMID: 16630896
  7. Structure and function of the nucleolus in the spotlight.  |  Raska, I., et al. 2006. Curr Opin Cell Biol. 18: 325-34. PMID: 16687244
  8. The nucleolus: reviewing oldies to have new understandings.  |  Lo, SJ., et al. 2006. Cell Res. 16: 530-8. PMID: 16775624
  9. [Prognostic significance of nucleolar markers in chronic lymphocytic leukemia].  |  Loseva, MI., et al. 1990. Gematol Transfuziol. 35: 22-4. PMID: 2283022

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Nucleolar Marker Antibody (31C4)

sc-57947
500 µl supernatant
$322.00

Which nucleolar layer does this antibody stain in IF?

Asked by: mjwong
Thank you for your question. For assistance please contact Technical Service. Please call 800-457-3801 or email scbt@scbt.com.
Answered by: BlakeJ
Date published: 2025-12-08

What is the concentration of Nucleolar Marker (31C4): sc-57947 monoclonal antibody?

Asked by: DefinitelyNotMatt
Thank you for your question. The concentration of Nucleolar Marker (31C4): sc-57947 has not been characterized. We provide this antibody as 250 µl of supernatant
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Band of interest observed in WB in yeastBand of interest observed in WB in yeast cell extract. -SCBT QC
Date published: 2015-02-23
Rated 5 out of 5 by from IF publishable data with soybean root meristematicIF publishable data with soybean root meristematic cells - SCBT Publication Review
Date published: 2014-02-04
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Nucleolar Marker Antibody (31C4) is rated 5.0 out of 5 by 2.
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