NSF Antibody (B-9): sc-514931
- NSF Antibody (B-9) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 50-74 near the N-terminus of NSF of human origin
- recommended for detection of NSF of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NSF Antibody (B-9) for WB applications. These reagents are now offered in bundles with NSF Antibody (B-9) (see ordering information below).
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NSF Antibody (B-9) is a mouse monoclonal IgG1 antibody that detects NSF in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NSF, or N-ethylmaleimide-sensitive factor, plays a crucial role in the process of membrane fusion, which is essential for various cellular functions, including neurotransmitter release and vesicle trafficking. NSF (B-9) antibody targets a protein primarily located in the cytoplasm, where NSF interacts with soluble NSF attachment proteins (SNAPs) and syntaxins to facilitate the assembly of the SNARE complex, a key component in the exocytosis pathway. Proper functioning of NSF is vital for maintaining synaptic transmission and cellular communication, making NSF a significant target for studying neurodegenerative diseases and other disorders related to vesicular transport. Anti-NSF antibody (B-9) provides a reliable tool for researchers aiming to explore the dynamics of membrane fusion and the intricate signaling pathways that govern cellular interactions.
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NSF Antibody (B-9) References:
- NSF regulates membrane traffic along multiple pathways in Paramecium. | Kissmehl, R., et al. 2002. J Cell Sci. 115: 3935-46. PMID: 12244131
- Interaction of SNAREs with ArfGAPs precedes recruitment of Sec18p/NSF. | Schindler, C. and Spang, A. 2007. Mol Biol Cell. 18: 2852-63. PMID: 17522384
- Risk of nephrogenic systemic fibrosis (NSF) in oncology patients receiving gadoxetic acid and updated risk of estimate of NSF in patients receiving gadoxetic acid with moderate and severe renal impairment. | Gauthier, ID., et al. 2022. Abdom Radiol (NY). 47: 1196-1201. PMID: 34997298
- After their membrane assembly, Sec18 (NSF) and Sec17 (SNAP) promote membrane fusion. | Song, H., et al. 2024. Mol Biol Cell. 35: ar150. PMID: 39475713
- An NSF-like ATPase, p97, and NSF mediate cisternal regrowth from mitotic Golgi fragments. | Rabouille, C., et al. 1995. Cell. 82: 905-14. PMID: 7553851
- Localization of human and mouse N-ethylmaleimide-sensitive factor (NSF) gene: a two-domain member of the AAA family that is involved in membrane fusion. | Hoyle, J., et al. 1996. Mamm Genome. 7: 850-2. PMID: 8875895
- The roles of NSF, SNAPs and SNAREs during membrane fusion. | Woodman, PG. 1997. Biochim Biophys Acta. 1357: 155-72. PMID: 9223620
- SNAREs and NSF in targeted membrane fusion. | Hay, JC. and Scheller, RH. 1997. Curr Opin Cell Biol. 9: 505-12. PMID: 9261050
- Regulation of neurotransmitter release kinetics by NSF. | Schweizer, FE., et al. 1998. Science. 279: 1203-6. PMID: 9469810
- NSF binding to GluR2 regulates synaptic transmission. | Nishimune, A., et al. 1998. Neuron. 21: 87-97. PMID: 9697854
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NSF Antibody (B-9) | sc-514931 | 200 µg/ml | $322.00 | |||
NSF Antibody (B-9): m-IgG Fc BP-HRP Bundle | sc-541012 | 200 µg Ab; 10 µg BP | $361.00 | |||
NSF Antibody (B-9): m-IgG1 BP-HRP Bundle | sc-542528 | 200 µg Ab; 20 µg BP | $361.00 | |||
NSF (B-9) Neutralizing Peptide | sc-514931 P | 100 µg/0.5 ml | $69.00 |