Molecular structure of NSC 185058, CAS Number: 39122-38-8
NSC 185058 (CAS 39122-38-8)
CAS Number:
39122-38-8
Molecular Weight:
215.3
Molecular Formula:
C11H9N3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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NSC 185058 (CAS 39122-38-8) References
- Inflammasome components coordinate autophagy and pyroptosis as macrophage responses to infection. | Byrne, BG., et al. 2013. mBio. 4: e00620-12. PMID: 23404401
- A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B. | Bosc, D., et al. 2018. Sci Rep. 8: 11653. PMID: 30076329
- Autophagy therapeutics: preclinical basis and initial clinical studies. | Zhan, L., et al. 2018. Cancer Chemother Pharmacol. 82: 923-934. PMID: 30225602
- Activity-Based Protein Profiling Identifies ATG4B as a Key Host Factor for Enterovirus 71 Proliferation. | Sun, Y., et al. 2019. J Virol. 93: PMID: 31554687
- Deacetylation of ATG4B promotes autophagy initiation under starvation. | Sun, L., et al. 2022. Sci Adv. 8: eabo0412. PMID: 35921421
- The LC3B FRET biosensor monitors the modes of action of ATG4B during autophagy in living cells. | Gökerküçük, EB., et al. 2023. Autophagy. 19: 2275-2295. PMID: 36814061
- Synthetic lethal screening identifies existing drugs with selective viability effects on Neurofibromatosis type-1 model systems[J]. | Wang Y, Stevens M, Mandigo T R. 2021: bioRxiv,.12. 20.: 473481.
- Autophagy, but not proteolysis, may aid in muscle protein synthesis[C]/ | Lewis M H, Ryan P J, Stanelle S T,. 2022. International Journal of Exercise Science:Conference Proceedings., 2(14):: 66.
- Insulin-induced Increase in Anabolic Capacity is Blunted by Autophagic Inhibition in L6 Myotubes[C] | Stanelle S T, Ryan P J, Lewis M H,. 2022. /International Journal of Exercise Science: Conference Proceedings., 2(14):: 65.
- Autophagy is Required for the Anabolic Response to Muscle Contraction[C] | Ryan P J, Stanelle S T, Lewis M H,. 2022,. International Journal of Exercise Science: Conference Proceedings. 2(14):: 62.
Inhibitor of:
5430411K18Rik, Atg10, Atg4b, BECN1, ISG20, MAP LC3α, NRBF2, PLEKHF1, Ppil3, TMEM49, TRIM16, and VPS37D.Activator of:
Atg4C, and GABARAPL2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NSC 185058, 1 mg | sc-507531 | 1 mg | $85.00 |