Date published: 2026-4-28

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NSC 146109 hydrochloride (CAS 59474-01-0)

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Alternate Names:
(10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride
Application:
NSC 146109 hydrochloride is an antitumor activator of p53-dependent transcription
CAS Number:
59474-01-0
Molecular Weight:
316.85
Molecular Formula:
C17H16N2S•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases the level of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay


NSC 146109 hydrochloride (CAS 59474-01-0) References

1. Dolma, S., et al. 2003. Cancer Cell. 3: 285-396.
2. Berkson, R.G., et al. 2005. Int. J. Cancer. 115: 701-710.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

NSC 146109 hydrochloride, 10 mg

sc-203652
10 mg
$160.00