Date published: 2025-11-1

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NPY 5RA972 (CAS 439861-56-0)

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Alternate Names:
N-[4-Methyl-9-(1-methylethyl)-9H-carbazol-3-yl]-4-morpholinecarboxamide
Application:
NPY 5RA972 is a potent and selective NPY5-R antagonist
CAS Number:
439861-56-0
Molecular Weight:
351.44
Molecular Formula:
C21H25N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

NPY 5RA972 is a neuropeptide Y (NPY) receptor antagonist. It is a small molecule that binds to the NPY receptor and blocks its activity. NPY receptors are G protein-coupled receptors that are involved in the regulation of energy balance, and stress responses. By blocking the NPY receptor, NPY 5RA972 can modulate these physiological processes. NPY 5RA972 is being studied for its potential role in the regulation of appetite. NPY 5RA972 is a promising target aimed at addressing the global health burden of obesity and its associated complications.


NPY 5RA972 (CAS 439861-56-0) References

  1. Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses.  |  Corrigan, CJ., et al. 2011. J Allergy Clin Immunol. 128: 116-24. PMID: 21570719
  2. Neuropeptide Y induces potent migration of human immature dendritic cells and promotes a Th2 polarization.  |  Buttari, B., et al. 2014. FASEB J. 28: 3038-49. PMID: 24699455
  3. Neuropeptide Y Stimulates Proliferation and Migration of Vascular Smooth Muscle Cells from Pregnancy Hypertensive Rats via Y1 and Y5 Receptors.  |  Zhang, P., et al. 2015. PLoS One. 10: e0131124. PMID: 26131716

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

NPY 5RA972, 10 mg

sc-295945
10 mg
$340.00
US: Only available in the US

NPY 5RA972, 50 mg

sc-295945A
50 mg
$850.00
US: Only available in the US