Molecular structure of NP-LLL-VS
NP-LLL-VS
Application:
NP-LLL-VS is used to prepare radiolabeled 125I-NIP-L3VS
Molecular Weight:
596.7
Molecular Formula:
C28H44N4O8S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
NP-LLL-VS is an intermediate that can be used to prepare radiolabeled 125I-NIP-L3VS for proteasome inhibition studies.
NP-LLL-VS References
- Global analysis of proteasomal substrate specificity using positional-scanning libraries of covalent inhibitors. | Nazif, T. and Bogyo, M. 2001. Proc Natl Acad Sci U S A. 98: 2967-72. PMID: 11248015
- Binding of hydrophobic peptides to several non-catalytic sites promotes peptide hydrolysis by all active sites of 20 S proteasomes. Evidence for peptide-induced channel opening in the alpha-rings. | Kisselev, AF., et al. 2002. J Biol Chem. 277: 22260-70. PMID: 11927581
- Applications for chemical probes of proteolytic activity. | Bogyo, M., et al. 2004. Curr Protoc Protein Sci. Chapter 21: 21.17.1-21.17.35. PMID: 18429259
- Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors. | Bogyo, M., et al. 1997. Proc Natl Acad Sci U S A. 94: 6629-34. PMID: 9192616
- Proteasome function is dispensable under normal but not under heat shock conditions in Thermoplasma acidophilum. | Ruepp, A., et al. 1998. FEBS Lett. 425: 87-90. PMID: 9541012
Inhibitor of:
Protease.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NP-LLL-VS, 500 µg | sc-222078 | 500 µg | $360.00 |