NP-40 Alternative is an alternative form of Nonidet P-40, which functions as a polyglycol ether (non-ionic) surfactant that is useful in isolating and purifying membrane proteins in two dimensional gel electrophoresis. Studies indicate that NP-40 Alternative can be employed to solubilize cerebral GABA receptors. Also NP-40 Alternative is an efficient tool to study breast cancer by functioning as a solubilizing agent interacting with membrane proteins and lipids. Furthermore, Nonidet P-40 is beneficial in the extraction of MHC proteins and the zwitterionic detergent CHAPS (sc-29088). We also offer Nonidet® P40 (substitute)(sc-29102).
1. Ripoche, P., et al. 1982. Biochim. Biophys. Acta. 693: 497-502. PMID: 6984343 2. Ito, Y. and Kuriyama, K. 1982. Brain Res. 236: 351-364. PMID: 6279240 3. Stephens, R.E. 1985. J. Cell Biol. 100: 1082-1090. PMID: 3980579 4. Schraag, B., et al. 1993. Anal. Biochem. 211: 233-239. PMID: 7686354
Soluble in water (25 mg/ml), and Aqueous buffers.
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For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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NP-40 Alternative (CAS 9016-45-9)
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