Molecular structure of Norneo Sildenafil, CAS Number: 371959-09-0
Norneo Sildenafil (CAS 371959-09-0)
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Alternate Names:
5-[2-Ethoxy-5-(1-piperidinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one
Application:
Norneo Sildenafil is an analog of Sildenafil and potential PDE5 inhibitor
CAS Number:
371959-09-0
Molecular Weight:
459.56
Molecular Formula:
C22H29N5O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Norneo Sildenafil is an analog of Sildenafil (sc-338584). Sildenafil is a selective inhibitor of the type 5 cGMP phosphodiesterase (PDE5 inhibitor) which catalyzes the hydrolysis of 3′,5′-cyclic guanosine monophosphate (cGMP). As a PDE5 inhibitor, Sildenafil has been reported to enhance neuro-, synapto- and angiogenesis in rat models of stroke and also is reported to be a mild vasodilator. Sildenafil has also been shown to prevent indomethacin-induced small intestinal ulceration formation through an NO/cGMP- dependent mechanism.
Norneo Sildenafil (CAS 371959-09-0) References
- Comparison of drug detection by three quadrupole time-of-flight mass spectrometry platforms. | Marin, SJ., et al. 2015. J Anal Toxicol. 39: 89-95. PMID: 25505058
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Norneo Sildenafil, 5 mg | sc-212414 | 5 mg | $326.00 |