Molecular structure of Norharmane hydrochloride, CAS Number: 7259-44-1
Norharmane hydrochloride (CAS 7259-44-1)
Alternate Names:
β-Carboline; 9H-Pyrido(3,4-b)indole
Application:
Norharmane hydrochloride is Inhibitor of IDO (indoleamine 2,3-dioxygenase)
CAS Number:
7259-44-1
Molecular Weight:
204.66
Molecular Formula:
C11H8N2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Norharmane hydrochloride, explored its interaction with DNA and other nucleic acids. Norharmane Hydrochloride is significant in the field of toxicology. In analytical chemistry, Norharmane hydrochloride is employed as a standard in fluorescence spectroscopy and mass spectrometry to develop and refine detection techniques for similar compounds. Norharmane hydrochloride is also applied in the exploration of its photophysical properties, which are for applications in optical materials and sensors.
Norharmane hydrochloride (CAS 7259-44-1) References
- Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. | Villégier, AS., et al. 2006. Neuropsychopharmacology. 31: 1704-13. PMID: 16395299
- A newly developed assay for the quantitative determination of antimicrobial (anticyanobacterial) activity of both hydrophilic and lipophilic test compounds without any restriction. | Volk, RB. 2008. Microbiol Res. 163: 161-7. PMID: 16730964
- Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats. | Guillem, K., et al. 2006. Eur J Neurosci. 24: 3532-40. PMID: 17229101
- Sustained inhibition of brotizolam induced anterograde amnesia by norharmane and retrograde amnesia by L-glutamic acid in mice. | Anand, A., et al. 2007. Behav Brain Res. 182: 12-20. PMID: 17561282
- Reinforcing and neural activating effects of norharmane, a non-nicotine tobacco constituent, alone and in combination with nicotine. | Arnold, MM., et al. 2014. Neuropharmacology. 85: 293-304. PMID: 24907588
- Effects of adolescent treatment with nicotine, harmane, or norharmane in male Sprague-Dawley rats. | Goodwin, AK., et al. 2015. Neurotoxicol Teratol. 47: 25-35. PMID: 25450662
- The modulatory action of harmane on serotonergic neurotransmission in rat brain. | Abu Ghazaleh, H., et al. 2015. Brain Res. 1597: 57-64. PMID: 25498864
- Catalytic activity of human indoleamine 2,3-dioxygenase (hIDO1) at low oxygen. | Kolawole, AO., et al. 2015. Arch Biochem Biophys. 570: 47-57. PMID: 25712221
- β-Carbolines found in cigarette smoke elevate intracranial self-stimulation thresholds in rats. | Harris, AC., et al. 2020. Pharmacol Biochem Behav. 198: 173041. PMID: 32926882
- Tremorigenic effect and inhibition of tryptamine and serotonin receptor binding by beta-carbolines. | Airaksinen, MM., et al. 1987. Pharmacol Toxicol. 60: 5-8. PMID: 3562389
- Ethyl beta-carboline-3-carboxylate antagonizes the inhibitory effect of diazepam on the crossed extensor reflex. | Kawasaki, K. and Matsushita, A. 1983. Jpn J Pharmacol. 33: 694-7. PMID: 6620736
- Cytotoxic and non-cytotoxic exometabolites of the cyanobacterium Nostoc insulare | Rainer-B. Volk & Sabine Mundt. (2007). Journal of Applied Phycology. volume 19,: pages55–62.
Inhibitor of:
IDO.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Norharmane hydrochloride, 100 mg | sc-253201 | 100 mg | $33.00 | |||
Norharmane hydrochloride, 1 g | sc-253201A | 1 g | $224.00 |