Date published: 2025-10-21
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Norethynodrel (CAS 68-23-5)

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Alternate Names:
(17α)-17-hydroxy-19-Norpregn-5(10)-en-20-yn-3-one
CAS Number:
68-23-5
Molecular Weight:
298.42
Molecular Formula:
C20H26O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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SDS & Certificate of Analysis

Norethynodrel is a synthetic progestin hormone. It interacts with progesterone receptors, effectively suppressing the production of other hormones. It is a 19-nortestosterone analog, which are a class of molecules characterized by the removal of the methyl group at the 19th carbon of the testosterone molecule. Norethynodrel serves as an interesting case study in the field of steroid synthesis and hormone analog development. It has served as a model compound for studying the relationship between chemical structure and hormonal activity.


Norethynodrel (CAS 68-23-5) References

  1. The use of norethynodrel (enovid) in clinical practice.  |  KORN, GW. 1961. Can Med Assoc J. 84: 584-7. PMID: 13753182
  2. Inherent estrogenicity of norethindrone and norethynodrel: comparison with other synthetic progestins and progesterone.  |  PAULSEN, CA., et al. 1962. J Clin Endocrinol Metab. 22: 1033-9. PMID: 13942007
  3. THE USE OF NORETHYNODREL IN PSYCHOTIC FEMALES.  |  SWANSON, DW., et al. 1964. Am J Psychiatry. 120: 1101-3. PMID: 14144433
  4. THE LINK BETWEEN NORETHYNODREL AND THROMBOEMBOLISM.  |  ROSENBERG, M. 1964. Am J Obstet Gynecol. 90: 745-6. PMID: 14233662
  5. NORETHYNODREL WITH MESTRANOL IN TREATMENT OF RHEUMATOID ARTHRITIS.  |  GILBERT, M., et al. 1964. JAMA. 190: 235. PMID: 14246596
  6. Metabolism of the synthetic progestogen norethynodrel by human ketosteroid reductases of the aldo-keto reductase superfamily.  |  Jin, Y., et al. 2012. J Steroid Biochem Mol Biol. 129: 139-44. PMID: 22210085
  7. Teratogenic and other effects produced in mice by norethynodrel and its 3-hydroxymetabolites.  |  Gidley, JT., et al. 1970. Teratology. 3: 339-44. PMID: 4156810
  8. The influence of norethynodrel on the hypophysis.  |  Baker, BL. and Yu, YY. 1970. Proc Soc Exp Biol Med. 134: 107-12. PMID: 4316380
  9. In vitro metabolism of 6,7-3H) norethynodrel in the human endometrium and the myometrium.  |  Murugesan, K., et al. 1973. Acta Endocrinol (Copenh). 74: 576-91. PMID: 4800856
  10. Norethynodrel metabolites in human plasma and urine.  |  Cook, CE., et al. 1972. J Pharmacol Exp Ther. 183: 197-205. PMID: 5080031
  11. Influence of norethynodrel with mestranol on intraocular pressure in glaucoma. II. A controlled double-blind study.  |  Meyer, EJ., et al. 1966. Arch Ophthalmol. 75: 771-3. PMID: 5327793
  12. Effects of norethynodrel and mestranol on endometrial and vaginal enzymatic activities in mice.  |  Chang, YS. and Russfield, AB. 1968. Am J Obstet Gynecol. 102: 736-44. PMID: 5684547
  13. Influence of norethynodrel with mestranol on intraocular pressure in glaucoma.  |  Meyer, EJ., et al. 1966. Arch Ophthalmol. 75: 157-61. PMID: 5903799

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Norethynodrel, 2.5 mg

sc-478776
2.5 mg
$398.00
1-800-457-3801
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