Norbornane (CAS 279-23-2)
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Norbornane is a bridged bicyclic hydrocarbon that serves as a key structural motif in the study of conformational analysis and strain energy in organic chemistry. It is a saturated compound, consisting of a cyclohexane ring "fused" with a cyclopentane ring, which provides a unique framework for investigating the effects of angular strain on chemical reactivity and stability. Norbornane′s rigid bicyclic structure is also an area of interest in materials science, where it is used to explore the synthesis of novel polymers and the incorporation of rigid units into polymer backbones to affect physical properties like glass transition temperature and tensile strength. Additionally, norbornane is a starting material for the synthesis of many other norbornane derivatives, which are explored for their potential utility in a range of applications, including the design of new organic compounds for materials science and the synthesis of natural products. Its role in the development of host-guest chemistry is also significant, as norbornane-based compounds can act as building blocks for molecular cages and other supramolecular structures.
Norbornane (CAS 279-23-2) References
- Two new conformationally restricted 4,5-dihydroxynorvaline analogues with a norbornane skeleton. | Buñuel, E., et al. 2000. Acta Crystallogr C. 56 (Pt 5): 587-91. PMID: 10851628
- Study of the conformational profile of the norbornane analogues of phenylalanine. | Cordomí, A., et al. 2002. J Pept Sci. 8: 253-66. PMID: 12093002
- General synthesis of unsymmetrical norbornane scaffolds as inducers for hydrogen bond interactions in peptides. | Hackenberger, CP., et al. 2004. J Org Chem. 69: 739-43. PMID: 14750799
- The band 12 issue in the electron momentum spectra of norbornane: a comparison with additional Green's Function calculations and ultraviolet photoemission measurements. | Knippenberg, S., et al. 2005. J Phys Chem A. 109: 4267-73. PMID: 16833755
- C-H bond dissociation enthalpies in norbornane. An experimental and computational study. | Nunes, PM., et al. 2008. Org Lett. 10: 1613-6. PMID: 18348570
- Ethanolysis of N-substituted norbornane epoxyimides: discovery of diverse pathways depending on substituent's character. | Petrova, T., et al. 2010. Org Biomol Chem. 8: 2142-57. PMID: 20401391
- Novel substituted 9-norbornylpurines and their activities against RNA viruses. | Sála, M., et al. 2012. Bioorg Med Chem Lett. 22: 1963-8. PMID: 22310228
- Synthesis and evaluation of cationic norbornanes as peptidomimetic antibacterial agents. | Hickey, SM., et al. 2015. Org Biomol Chem. 13: 6225-41. PMID: 25958967
- Structure of fenchone by broadband rotational spectroscopy. | Loru, D., et al. 2016. J Chem Phys. 145: 074311. PMID: 27544109
- Norbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membrane. | Hickey, SM., et al. 2018. Eur J Med Chem. 160: 9-22. PMID: 30316060
- Open and rearranged norbornane derived polycyclic cage molecules as potential neuroprotective agents through attenuation of MPP+- and calcium overload-induced excitotoxicity in neuroblastoma SH-SY5Y cells. | Egunlusi, AO., et al. 2020. Eur J Med Chem. 204: 112617. PMID: 32717484
- Efficient Production of Epoxy-Norbornane from Norbornene by an Engineered P450 Peroxygenase. | Yan, Y., et al. 2023. Chembiochem. 24: e202200529. PMID: 36354378
- [Ethylamine derivatives of cineol and norbornane]. | Mariani, E. and Schenone, P. 1974. Farmaco Sci. 29: 113-9. PMID: 4426377
- Development of neural network simulator for structure--activity correlation of molecules (NECO). Prediction of endo/exo substitution of norbornane derivatives and of carcinogenic activity of PAHs from 13C-NMR shifts. | Isu, Y., et al. 1996. J Chem Inf Comput Sci. 36: 286-93. PMID: 8882811
- [Changes in the density of GABAA receptor chloride channels in rodent brain induced by norbornane]. | Golovko, AI., et al. 1996. Biull Eksp Biol Med. 122: 14-6. PMID: 9303688
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Norbornane, 10 g | sc-236192 | 10 g | $339.00 |