Molecular structure of NOR-4, CAS Number: 163180-50-5
NOR-4 (CAS 163180-50-5)
Alternate Names:
FR 144420
Application:
NOR-4 is a nitric oxide (NO) donor
CAS Number:
163180-50-5
Purity:
≥97%
Molecular Weight:
306.32
Molecular Formula:
C14H18N4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
NOR-4 is a nitric oxide (NO) donating compound which releases NO in a rate-controlled manner. This compound is described to have an NO release half-life of 60 minutes in solution. NOR-4 has been demonstrated as a useful tool for investigating the in vitro actions of NO. NORs release NO at a steady rate, although the mechanism of release is not yet known.
NOR-4 (CAS 163180-50-5) References
- Kinetic characterization of the nitric oxide toxicity for PC12 cells: effect of half-life time of NO release. | Yamamoto, T., et al. 2000. Eur J Pharmacol. 397: 25-33. PMID: 10844095
- Role of c-Myc in nitric oxide-mediated suppression of cytochrome P450 3A4. | Watabe, M., et al. 2003. Life Sci. 74: 99-108. PMID: 14575816
- Dipyridamole increases human red blood cell deformability. | Saniabadi, AR., et al. 1992. Eur J Clin Pharmacol. 42: 651-4. PMID: 1623907
- Nitric oxide and cGMP protein kinase (cGK) regulate dendritic-cell migration toward the lymph-node-directing chemokine CCL19. | Giordano, D., et al. 2006. Blood. 107: 1537-45. PMID: 16249377
- Role of new agents affecting NO/cGMP pathway on ovalbumin-sensitized guinea pig trachea. | Parlak, A., et al. 2012. Exp Lung Res. 38: 420-6. PMID: 23030645
- Modulation of Hyperosmotic and Immune-Induced Disruption of the Blood-Brain Barrier by the Nitric Oxide System. | Hasarmeh, M., et al. 2016. Neuroimmunomodulation. 23: 1-7. PMID: 26670748
- FR144420, a novel, slow, nitric oxide-releasing agent. | Kita, Y., et al. 1995. Eur J Pharmacol. 275: 125-30. PMID: 7796846
- Oral biological activities of spontaneous nitric oxide releasers are accounted for by their nitric oxide-releasing rates and oral absorption manners. | Kita, Y., et al. 1996. J Pharmacol Exp Ther. 276: 421-5. PMID: 8632305
- Antianginal effects of FR144420, a novel slow nitric oxide-releasing agent. | Hirasawa, Y., et al. 1996. Eur J Pharmacol. 303: 55-9. PMID: 8804911
- (-)-Deprenyl protects human dopaminergic neuroblastoma SH-SY5Y cells from apoptosis induced by peroxynitrite and nitric oxide. | Maruyama, W., et al. 1998. J Neurochem. 70: 2510-5. PMID: 9603216
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NOR-4, 5 mg | sc-202739 | 5 mg | $65.00 | |||
NOR-4, 10 mg | sc-202739A | 10 mg | $125.00 |