Nop5p Antibody (34B12): sc-57942

Nop5p Antibody (34B12) is a mouse monoclonal IgG3 antibody that detects the Nop5p protein of S. cerevisiae origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-Nop5p antibody (34B12) is available as the non-conjugated format. Nop5p plays a crucial role in the nucleolus, where Nop5p is involved in the assembly of small nucleolar ribonucleoprotein particles (snoRNPs) that are essential for the processing of pre-ribosomal RNA (pre-rRNA). Nop5p interacts with small nucleolar RNAs (snoRNAs) to facilitate the modification and maturation of rRNA, which is vital for ribosome biogenesis and, consequently, protein synthesis in the cell. Proper functioning of Nop5p is critical for maintaining cellular viability, as defects in ribosomal RNA processing can lead to impaired protein synthesis and cellular dysfunction. Nop5p′s structural similarity to vertebrate fibrillarin highlights evolutionary conservation and underscores importance across different species. Anti-Nop5p antibody (34B12) enables valuable insights into the mechanisms of ribosome assembly and the intricate processes governing cellular function in S. cerevisiae.

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Nop5p Antibody (34B12) References:

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