NOP17 Antibody (C-9): sc-390810
- NOP17 Antibody (C-9) is a mouse monoclonal mouse IgG1 λ λ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 98-113 within an internal region of NOP17 of human origin
- recommended for detection of NOP17 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for NOP17 Antibody (C-9) for WB applications. These reagents are now offered in bundles with NOP17 Antibody (C-9) (see ordering information below).
QUICK LINKS
SEE ALSO...
NOP17 Antibody (C-9) is a mouse monoclonal IgG1 antibody that detects NOP17 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NOP17, also known as PIH1D1, is a phylogenetically conserved protein that plays a crucial role in the processing of pre-ribosomal RNA (pre-rRNA) by associating with a specific class of small nucleolar RNAs (snoRNAs) during ribosomal biogenesis. These snoRNAs are integral components of ribonucleoprotein particles that are localized to the nucleolus, where they facilitate the modification and maturation of rRNA. NOP17 consists of 290 amino acids and is inherently unstable; however, NOP17 gains stability through interaction with heat shock proteins HSP 90α and HSP 90β. Furthermore, NOP17 interacts with the core box C/D snoRNP protein Nop58, which suggests an essential function in mediating the nucleolar retention and proper assembly of box C/D snoRNP complexes. Notably, mutations in the NOP17 gene can result in a temperature-sensitive phenotype, leading to the delocalization of critical NOP proteins necessary for snoRNP assembly, thereby underscoring NOP17′s importance in maintaining ribosomal RNA processing and overall cellular function. Anti-NOP17 antibody (C-9) is an invaluable tool for researchers studying ribosomal biogenesis and the molecular mechanisms underlying RNA processing.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NOP17 Antibody (C-9) | sc-390810 | 200 µg/ml | $322.00 | |||
NOP17 Antibody (C-9): m-IgG Fc BP-HRP Bundle | sc-540859 | 200 µg Ab; 10 µg BP | $361.00 | |||
NOP17 Antibody (C-9): m-IgG1 BP-HRP Bundle | sc-542422 | 200 µg Ab; 20 µg BP | $361.00 | |||
NOP17 (C-9) Neutralizing Peptide | sc-390810 P | 100 µg/0.5 ml | $69.00 |