Nonyl-β-D-1-thiomaltoside (CAS 148565-55-3)

Nonyl-β-D-1-thiomaltoside, a nonionic detergent, is utilized extensively in scientific research for its unique properties and diverse applications. Its mechanism of action involves disrupting lipid-protein interactions in biological membranes, facilitating solubilization and stabilization of membrane proteins. In research, this chemical has been pivotal in the purification and structural characterization of membrane proteins, particularly integral membrane proteins such as receptors, ion channels, and transporters. Due to its mild detergent properties, it effectively solubilizes membrane proteins while maintaining their native structure and functionality, making it indispensable in various biochemical and biophysical studies. Additionally, nonyl-β-D-1-thiomaltoside has been instrumental in the development of novel drug delivery systems and biomimetic membranes for studying membrane protein-lipid interactions and membrane-related processes. Its compatibility with various analytical techniques, including spectroscopy, chromatography, and crystallography, further enhances its utility in elucidating the structure-function relationships of membrane proteins. Moreover, its biocompatibility and low cytotoxicity make it suitable for applications in cell biology and biotechnology, highlighting its significance in advancing our understanding of membrane biology and facilitating the development of biotechnological innovations.