Nonyl b-D-maltopyranoside (CAS 106402-05-5)

Nonyl β-D-maltopyranoside is a nonionic surfactant widely used in the field of biochemistry for its role in stabilizing membrane proteins and facilitating their study in a more native-like environment. This surfactant′s structure, featuring a nonyl hydrophobic tail linked to a hydrophilic maltopyranoside headgroup, allows it to effectively solubilize membrane proteins without disrupting their structure, crucial for functional and structural analysis. The maltopyranoside headgroup is particularly mild on proteins, reducing the risk of denaturation and maintaining functional activity, which is essential for detailed biochemical assays. Nonyl β-D-maltopyranoside is favored in research involving the purification and crystallization of membrane proteins, providing a clear advantage in the study of protein-ligand interactions and enzymatic mechanisms. Its application extends to the formation of micelles and liposomes used in biophysical studies to mimic cellular environments. This compound′s utility in these applications highlights its importance in advancing our understanding of membrane protein structures and functions, contributing significantly to the field of molecular biology by facilitating insights into membrane-associated processes and mechanisms.