Date published: 2026-4-25

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Nonoxynol, n=9 (CAS 26027-38-3)

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Application:
Nonoxynol, n=9 is a polyoxynol nonylpheyl
CAS Number:
26027-38-3
Purity:
≥98%
Molecular Weight:
616.82
Molecular Formula:
C33H60O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Nonoxynol, n=9, a surfactant compound extensively utilized in diverse industrial and biomedical applications, is synthesized through a chemical process involving the reaction of nonylphenol with ethylene oxide. The potential applications of Nonoxynol, n=9 as a spermicide and microbicide have been the subject of extensive research. Its efficacy in combating a broad spectrum of microorganisms, including bacteria, fungi, and viruses, has been demonstrated. Moreover, Nonoxynol, n=9 finds utility as a detergent and emulsifying agent across various industrial sectors. The mechanism of action employed by Nonoxynol, n=9 involves the disruption of the cell membrane of microorganisms. By inserting itself into the lipid bilayer of the cell membrane, it induces destabilization. Consequently, the intracellular contents are released, leading to the eventual demise of the microorganism.


Nonoxynol, n=9 (CAS 26027-38-3) References

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  3. Advances in HIV microbicide development.  |  Olsen, JS., et al. 2011. Future Med Chem. 3: 2101-16. PMID: 22098355
  4. Expression, regulation, and function of drug transporters in cervicovaginal tissues of a mouse model used for microbicide testing.  |  Zhou, T., et al. 2016. Biochem Pharmacol. 116: 162-75. PMID: 27453435
  5. In vitro anti-HIV activity of some Indian medicinal plant extracts.  |  Palshetkar, A., et al. 2020. BMC Complement Med Ther. 20: 69. PMID: 32143607
  6. 'Secondary prevention' against female HPV infection: literature review of the role of carrageenan.  |  Calagna, G., et al. 2020. Expert Rev Anti Infect Ther. 18: 865-874. PMID: 32552158
  7. Aryl glyoxal: a prime synthetic equivalent for multicomponent reactions in the designing of oxygen heterocycles.  |  Sheikh, AR., et al. 2023. RSC Adv. 13: 11652-11684. PMID: 37063730
  8. An updated review of environmental estrogen and androgen mimics and antagonists.  |  Sonnenschein, C. and Soto, AM. 1998. J Steroid Biochem Mol Biol. 65: 143-50. PMID: 9699867

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Nonoxynol, n=9, 50 g

sc-204821
50 g
$94.00

Nonoxynol, n=9, 100 g

sc-204821A
100 g
$160.00