Molecular structure of NOC-7, CAS Number: 146724-84-7
NOC-7 (CAS 146724-84-7)
See product citations (5)
Alternate Names:
3-(2-Hydroxy-1-methyl-2-nitrosohydrazino)-N-methyl-1-propanamine
Application:
NOC-7 is a quick-releasing NO donor
CAS Number:
146724-84-7
Purity:
≥96%
Molecular Weight:
162.19
Molecular Formula:
C5H14N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
NOC-7 is a nitric oxide (NO) donor similar to NOC-5 (sc-202248) but with a much shorter half-life of NO release. Half-life (t½) in PBS, pH 7.4 is 10 minutes at 22°C. NOC-7 may act to be useful as a short-acting nitrovasodilator. NOC-7 is known to be relatively stable in alkaline solution (pH ≥10.0).
NOC-7 (CAS 146724-84-7) References
- Activation and inhibition of purified skeletal muscle calcium release channel by NO donors in single channel current recordings. | Suko, J., et al. 1999. Biochim Biophys Acta. 1451: 271-87. PMID: 10556582
- Differential effects of nitric oxide on the activity of prostaglandin endoperoxide H synthase-1 and -2 in vascular endothelial cells. | Onodera, M., et al. 2000. Prostaglandins Leukot Essent Fatty Acids. 62: 161-7. PMID: 10841038
- Standardization of nitric oxide aqueous solutions by modified Saltzman method. | Ohkawa, T., et al. 2001. Nitric Oxide. 5: 515-24. PMID: 11730358
- Dual effect of nitric oxide on cytosolic Ca2+ concentration and insulin secretion in rat pancreatic beta-cells. | Kaneko, Y., et al. 2003. Am J Physiol Cell Physiol. 284: C1215-22. PMID: 12529241
- Angiotensin II-induced modulation of endothelium-dependent relaxation in rabbit mesenteric resistance arteries. | Itoh, T., et al. 2003. J Physiol. 548: 893-906. PMID: 12651915
- Two distinct effects of cGMP on cytosolic Ca2+ concentration of rat pancreatic beta-cells. | Ishikawa, T., et al. 2003. J Pharmacol Sci. 91: 41-6. PMID: 12686729
- The construction of endothelial cellular biosensing system for the control of blood pressure drugs. | Kamei, K., et al. 2004. Biosens Bioelectron. 19: 1121-4. PMID: 15018968
- Expression and putative role of lactoseries carbohydrates present on NCAM in the rat primary olfactory pathway. | Storan, MJ., et al. 2004. J Comp Neurol. 475: 289-302. PMID: 15221946
- Nitric oxide regulates growth cone filopodial dynamics via ryanodine receptor-mediated calcium release. | Welshhans, K. and Rehder, V. 2007. Eur J Neurosci. 26: 1537-47. PMID: 17714493
- Effects of endogenous ligands on the biological role of human serum albumin in S-nitrosylation. | Ishima, Y., et al. 2007. Biochem Biophys Res Commun. 364: 790-5. PMID: 18273439
- Matrix metalloproteinase-2 mediates stretch-induced activation of skeletal muscle satellite cells in a nitric oxide-dependent manner. | Yamada, M., et al. 2008. Int J Biochem Cell Biol. 40: 2183-91. PMID: 18403250
- Reduction of nitric oxide catalyzed by hydroxylamine oxidoreductase from an anammox bacterium. | Irisa, T., et al. 2014. J Biosci Bioeng. 118: 616-21. PMID: 24996970
- Nitric oxide/nucleophile complexes inhibit the in vitro proliferation of A375 melanoma cells via nitric oxide release. | Maragos, CM., et al. 1993. Cancer Res. 53: 564-8. PMID: 8425188
- Fas-mediated apoptosis. | Nagata, S. 1996. Adv Exp Med Biol. 406: 119-24. PMID: 8910677
- Renal effects of a nitric oxide donor, NOC 7, in anesthetized rabbits. | Adachi, Y., et al. 1997. Eur J Pharmacol. 324: 223-6. PMID: 9145776
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NOC-7, 10 mg | sc-202249 | 10 mg | $210.00 |