NMT1 Antibody (E-9): sc-393702
- NMT1 Antibody (E-9) is a mouse monoclonal IgG1 κ NMT1 antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 146-179 within an internal region of NMT1 of human origin
- NMT1 Antibody (E-9) is recommended for detection of NMT1 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- Anti-NMT1 Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NMT1 Antibody (E-9) for WB applications. These reagents are now offered in bundles with NMT1 Antibody (E-9) (see ordering information below).
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NMT1 Antibody (E-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects NMT1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NMT1 (E-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NMT1 plays a critical role in the process of N-terminal myristoylation, a cotranslational lipid modification essential for proper targeting and function of numerous signaling proteins. This modification influences protein localization, stability, and interactions, thereby impacting various cellular processes such as signal transduction and membrane trafficking. NMT1, along with NMT2, is primarily found in the cytoplasm and is involved in adding a myristoyl group to N-terminal glycine residue of eukaryotic, fungal, and viral proteins. NMT1 is predominantly expressed in tissues such as heart, gut, kidney, liver, and placenta, highlighting significance in both normal physiology and potential pathophysiological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
NMT1 Antibody (E-9) References:
- Altered expression and localization of N-myristoyltransferase in experimentally induced rat model of ischemia-reperfusion. | Rajala, RV., et al. 2002. J Cell Biochem. 86: 509-19. PMID: 12210757
- Expression of methionine aminopeptidase 2, N-myristoyltransferase, and N-myristoyltransferase inhibitor protein 71 in HT29. | Selvakumar, P., et al. 2004. Biochem Biophys Res Commun. 322: 1012-7. PMID: 15336565
- Potential role of N-myristoyltransferase in pathogenic conditions. | Sharma, RK. 2004. Can J Physiol Pharmacol. 82: 849-59. PMID: 15573145
- Functional analysis of TbARL1, an N-myristoylated Golgi protein essential for viability in bloodstream trypanosomes. | Price, HP., et al. 2005. J Cell Sci. 118: 831-41. PMID: 15687105
- N-myristoyltransferase 1 is essential in early mouse development. | Yang, SH., et al. 2005. J Biol Chem. 280: 18990-5. PMID: 15753093
- Expression of N-myristoyltransferase in human brain tumors. | Lu, Y., et al. 2005. Neurochem Res. 30: 9-13. PMID: 15756927
- Increased myocardial N-myristoyltransferase activity in rotenone model of Parkinsonism. | Pasha, MK., et al. 2005. Int J Mol Med. 15: 987-91. PMID: 15870904
- Characterization of a polyhistidine-tagged form of human myristoyl-CoA: protein N-myristoyltransferase produced in Escherichia coli. | McIlhinney, RA., et al. 1994. Eur J Biochem. 222: 137-46. PMID: 8200338
- Crystal structure of the anti-fungal target N-myristoyl transferase. | Weston, SA., et al. 1998. Nat Struct Biol. 5: 213-21. PMID: 9501915
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NMT1 Antibody (E-9) | sc-393702 | 200 µg/ml | $322.00 | |||
NMT1 Antibody (E-9): m-IgG Fc BP-HRP Bundle | sc-530547 | 200 µg Ab; 10 µg BP | $361.00 | |||
NMT1 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-524053 | 200 µg Ab, 40 µg BP | $361.00 | |||
NMT1 Antibody (E-9): m-IgG1 BP-HRP Bundle | sc-544121 | 200 µg Ab; 20 µg BP | $361.00 | |||
NMT1 Antibody (E-9) AC | sc-393702 AC | 500 µg/ml, 25% agarose | $424.00 | |||
NMT1 Antibody (E-9) HRP | sc-393702 HRP | 200 µg/ml | $322.00 | |||
NMT1 Antibody (E-9) FITC | sc-393702 FITC | 200 µg/ml | $336.00 | |||
NMT1 Antibody (E-9) PE | sc-393702 PE | 200 µg/ml | $349.00 | |||
NMT1 Antibody (E-9) Alexa Fluor® 488 | sc-393702 AF488 | 200 µg/ml | $364.00 | |||
NMT1 Antibody (E-9) Alexa Fluor® 546 | sc-393702 AF546 | 200 µg/ml | $364.00 | |||
NMT1 Antibody (E-9) Alexa Fluor® 594 | sc-393702 AF594 | 200 µg/ml | $364.00 | |||
NMT1 Antibody (E-9) Alexa Fluor® 647 | sc-393702 AF647 | 200 µg/ml | $364.00 | |||
NMT1 Antibody (E-9) Alexa Fluor® 680 | sc-393702 AF680 | 200 µg/ml | $364.00 | |||
NMT1 Antibody (E-9) Alexa Fluor® 790 | sc-393702 AF790 | 200 µg/ml | $364.00 | |||
NMT1 (E-9) Neutralizing Peptide | sc-393702 P | 100 µg/0.5 ml | $69.00 |