Nitroso(acetoxymethyl)methylamine (CAS 56856-83-8)
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Nitroso(acetoxymethyl)methylamine is a stable derivative of the dimethylnitrosoamine metabolite, a potent carcinogen. Nitroso(acetoxymethyl)methylamine has garnered significant interest in scientific research due to its potential applications. In laboratory experiments, it has been utilized to investigate the impact of nitrosamines on cells and explore the mechanism of action associated with nitrosamines. Moreover, it has been employed to study the effects of nitrosamines on enzymes, proteins, and gene expression. As an alkylating agent, it demonstrates the ability to form covalent bonds with DNA and other cellular components. These covalent bonds can induce structural and functional alterations in cellular components, potentially leading to changes in gene expression and cellular behavior.
Nitroso(acetoxymethyl)methylamine (CAS 56856-83-8) References
- 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone modulation of cytokine release in U937 human macrophages. | Rioux, N. and Castonguay, A. 2001. Cancer Immunol Immunother. 49: 663-70. PMID: 11258792
- Carcinogenicity of N-nitroso-acetoxymethyl-methylamine (acetoxymethyl-methylnitrosamine) after inhalation in rats. | Klein, RG. 1983. Toxicology. 27: 139-46. PMID: 6612744
- Stability of nitrosoacetoxymethylmethylamine in in vitro systems and in vivo and its excretion by the rat organism. | Frank, N., et al. 1980. Biochem Pharmacol. 29: 383-7. PMID: 7362651
- Selective induction of intestinal tumors in rats by methyl(acetoxymethyl)nitrosamine, an ester of the presumed reactive metabolite of dimethylnitrosamine. | Joshi, SR., et al. 1977. J Natl Cancer Inst. 58: 1531-5. PMID: 857039
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nitroso(acetoxymethyl)methylamine, 10 mg | sc-205770 | 10 mg | $115.00 | |||
Nitroso(acetoxymethyl)methylamine, 50 mg | sc-205770A | 50 mg | $462.00 |