NIH/3T3 Whole Cell Lysate: sc-2210

NIH/3T3 whole cell lysate is derived from the NIH/3T3 cell line, which was established from mouse embryonic fibroblasts. This lysate is widely used in scientific research to study cellular signaling, growth regulation, and oncogenic transformation. NIH/3T3 cells are known for their robust growth and susceptibility to transformation by oncogenes, making the lysate an essential tool for investigating mechanisms of cell cycle control, proliferation, and differentiation. Researchers utilize NIH/3T3 whole cell lysate to analyze key signaling pathways such as the Ras-MAPK/ERK, PI3K/Akt, and JAK/STAT pathways, which are crucial for regulating cell growth and survival. This lysate facilitates the study of protein expression, post-translational modifications, and the interactions between signaling molecules. It is also employed to investigate the effects of various chemical modulators on these signaling pathways, providing insights into the regulatory mechanisms of cellular behavior and oncogenesis. Recent research has leveraged NIH/3T3 whole cell lysate for proteomic and genomic analyses to identify novel proteins and signaling networks involved in cell growth and transformation. By offering detailed insights into the molecular and cellular mechanisms underlying cell proliferation and oncogenic processes, NIH/3T3 whole cell lysate remains a vital resource for advancing research in cell biology and cancer.

NIH/3T3 Whole Cell Lysate References:

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