Molecular structure of Nifursol, CAS Number: 16915-70-1
Nifursol (CAS 16915-70-1)
Application:
Nifursol is a nitrofuran antibiotic which inhibits Histomonas meleagridis
CAS Number:
16915-70-1
Purity:
≥98%
Molecular Weight:
365.21
Molecular Formula:
C12H7N5O9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Nifursol is a nitrofuran antibiotic which inhibits the growth of Histomonas meleagridis but is not lethal to the flagellated protozoan. In addition, Nifursol can be analyzed and detected in tissues using intact 3,5-dinitrosalicylic acid hydrazide side chains along with electron-capture GC, spectrophotometric detection, and HPLC with ultraviolet light detection. In tissues, it has been observed that Nifursol is tightly bound to proteins and requires basic solutions such as ammonia to break the bonds between the two.Nifursol, also referred to as histomon or RT 6912, is an antiprotozoal compound belonging to the class of organic compounds known as dinitrophenols. Nifursol is found in formulations specifically designed for histomoniasis prevention in poultry. This solid compound is classified as practically insoluble in water and relatively neutral.
Nifursol (CAS 16915-70-1) References
- Gas-liquid chromatographic determination of nifursol in frozen turkey tissues to ten parts per billion. | Frahm, LJ., et al. 1975. J Assoc Off Anal Chem. 58: 694-9. PMID: 1150608
- Analysis of nifursol residues in turkey and chicken meat using liquid chromatography-tandem mass spectrometry. | Vahl, M. 2005. Food Addit Contam. 22: 120-7. PMID: 15824001
- Multi-residue monitoring for the simultaneous determination of five nitrofurans (furazolidone, furaltadone, nitrofurazone, nitrofurantoine, nifursol) in poultry muscle tissue through the detection of their five major metabolites (AOZ, AMOZ, SEM, AHD, DNSAH) by liquid chromatography coupled to electrospray tandem mass spectrometry--in-house validation in line with Commission Decision 657/2002/EC. | Verdon, E., et al. 2007. Anal Chim Acta. 586: 336-47. PMID: 17386733
- Incidence of histomonosis in turkeys in France since the bans of dimetridazole and nifursol. | Callait-Cardinal, MP., et al. 2007. Vet Rec. 161: 581-5. PMID: 17965368
- Screening method for the detection of a range of nitrofurans in avian eyes by optical biosensor. | Thompson, CS., et al. 2011. Anal Chim Acta. 700: 177-82. PMID: 21742130
- Detection, accumulation, distribution, and depletion of furaltadone and nifursol residues in poultry muscle, liver, and gizzard. | Barbosa, J., et al. 2011. J Agric Food Chem. 59: 11927-34. PMID: 22011291
- Determination of furaltadone and nifursol residues in poultry eggs by liquid chromatography-electrospray ionization tandem mass spectrometry. | Barbosa, J., et al. 2012. J Agric Food Chem. 60: 4227-34. PMID: 22486660
- An unusual outbreak of histomonosis in a commercial turkey flock. | Popp, C., et al. 2012. Berl Munch Tierarztl Wochenschr. 125: 153-8. PMID: 22515034
- Determination of nitrofuran and chloramphenicol residues by high resolution mass spectrometry versus tandem quadrupole mass spectrometry. | Kaufmann, A., et al. 2015. Anal Chim Acta. 862: 41-52. PMID: 25682427
- Development of a multi-class method to determine nitroimidazoles, nitrofurans, pharmacologically active dyes and chloramphenicol in aquaculture products by liquid chromatography-tandem mass spectrometry. | Chen, D., et al. 2020. Food Chem. 311: 125924. PMID: 31865112
- Development and validation of a rapid LC-MS/MS method for the confirmatory analysis of the bound residues of eight nitrofuran drugs in meat using microwave reaction. | Regan, G., et al. 2022. Anal Bioanal Chem. 414: 1375-1388. PMID: 34816286
- Determination of nifursol in medicated animal feeds using high-performance liquid chromatography. Analytical Methods Committee. | . 1985. Analyst. 110: 1013-7. PMID: 4061847
- Prophylactic efficacy of nifursol against different levels of exposure to histomoniasis in turkeys 4 to 9 weeks of age. | Sullivan, TW., et al. 1972. Poult Sci. 51: 1956-9. PMID: 4676760
- Effect of cupric sulfate on the prophylactic efficacy of 2-acetylamino-5nitrothiazole, nifursol and ipronidazole against histomoniasis in turkeys. | Bowen, TE., et al. 1971. Poult Sci. 50: 1668-72. PMID: 5168319
- High pressure liquid chromatographic determination of nifursol in finished feeds. | George, GM., et al. 1981. J Assoc Off Anal Chem. 64: 969-72. PMID: 7275913
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nifursol, 25 g | sc-205769 | 25 g | $112.00 | |||
Nifursol, 100 g | sc-205769A | 100 g | $321.00 |