Molecular structure of Nifenazone, CAS Number: 2139-47-1
Nifenazone (CAS 2139-47-1)
Alternate Names:
1,5-Dimethyl-4-nicotinamido-2-phenyl-3-pyrazolone
Application:
Nifenazone is an analytical standard
CAS Number:
2139-47-1
Purity:
>98%
Molecular Weight:
308.33
Molecular Formula:
C17H16N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Nifenazone inhibits the activity of cyclooxygenase, an enzyme involved in the production of prostaglandins. Prostaglandins are lipid compounds that play a key role in the inflammatory response, and by inhibiting their production, nifenazone helps to reduce inflammation. Nifenazone is investigated for its potential role in modulating the immune response, as prostaglandins are involved in the regulation of immune function.
Nifenazone (CAS 2139-47-1) References
- Synthesis, characterization and analgesic activity of new 4-arylhydrazono-3-methoxymethyl-2-pyrazolin-5-ones. | Ergenç, N., et al. 2001. Arzneimittelforschung. 51: 118-24. PMID: 11258041
- Facile synthesis of fused pyrazolo[1,5-a]pyrimidinepyrazolo [1,5-a]triazines and N-sulphonamidopyrazoles as antiinflammatory. | Fathalla, OA., et al. 2003. Acta Pol Pharm. 60: 51-60. PMID: 12848368
- Detection of Radiation-Exposure Biomarkers by Differential Mobility Prefiltered Mass Spectrometry (DMS-MS). | Coy, SL., et al. 2010. Int J Mass Spectrom. 291: 108-117. PMID: 20305793
- Predictable and less predictable unwanted cardiac drugs effects: individual pre-disposition and transient precipitating factors. | Fabritz, L. and Kirchhof, P. 2010. Basic Clin Pharmacol Toxicol. 106: 263-8. PMID: 20470256
- Pd-catalyzed asymmetric allylic alkylation of pyrazol-5-ones with allylic alcohols: the role of the chiral phosphoric acid in C-O bond cleavage and stereocontrol. | Tao, ZL., et al. 2013. J Am Chem Soc. 135: 9255-8. PMID: 23734612
- The solvatochromic, spectral, and geometrical properties of nifenazone: a DFT/TD-DFT and experimental study. | Bani-Yaseen, AD. and Al-Balawi, M. 2014. Phys Chem Chem Phys. 16: 15519-26. PMID: 24954054
- Temporal endogenous gene expression profiles in response to lipid-mediated transfection. | Martin, TM., et al. 2015. J Gene Med. 17: 14-32. PMID: 25663588
- Virtual screening of plant compounds and nonsteroidal anti-inflammatory drugs for inhibition of quorum sensing and biofilm formation in Salmonella. | Almeida, FA., et al. 2018. Microb Pathog. 121: 369-388. PMID: 29763730
- Synthesis, characterization, molecular docking and biological activities of novel pyrazoline derivatives. | Turkan, F., et al. 2019. Arch Pharm (Weinheim). 352: e1800359. PMID: 31125504
- Pyrazolones Activate the Proteasome by Gating Mechanisms and Protect Neuronal Cells from β-Amyloid Toxicity. | Santoro, AM., et al. 2020. ChemMedChem. 15: 302-316. PMID: 31797568
- The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin. | Zhang, Y., et al. 2020. Nat Cell Biol. 22: 1332-1345. PMID: 33106653
- High-performance liquid chromatography systems for the analysis of analgesic and non-steroidal anti-inflammatory drugs in forensic toxicology. | Stevens, HM. and Gill, R. 1986. J Chromatogr. 370: 39-47. PMID: 3805219
- Photochemical decomposition of phenazone derivatives. Part 5(1): Isolation and identification of decomposition products in aqueous solution. | Marciniec, B. 1985. Pharmazie. 40: 30-3. PMID: 3991782
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nifenazone, 100 mg | sc-236175 | 100 mg | $235.00 |