Molecular structure of Nicotinic acid mononucleotide, CAS Number: 321-02-8
Nicotinic acid mononucleotide (CAS 321-02-8)
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Alternate Names:
3-Carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium
Application:
Nicotinic acid mononucleotide is can be used to study the phosphate-responsive signaling pathway in yeast
CAS Number:
321-02-8
Purity:
≥98 %
Molecular Weight:
335.20
Molecular Formula:
C11H14NO9P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Nicotinic acid mononucleotide can be used to study the phosphate-responsive signaling pathway in yeast and NAD(+) in yeast. It is also a substrate for NMN/NaMN adenylyltransferase (NMNAT). Nicotinic acid mononucleotide is synthesized through the Preiss-Handler pathway by the action of phosphoribosyltransferase enzyme on nicotinic acid 5-phosphoribosyl-1-pyrophosphate.
Nicotinic acid mononucleotide (CAS 321-02-8) References
- Reversed-phase high-performance liquid chromatography of nicotinic acid mononucleotide for measurement of quinolinate phosphoribosyltransferase. | Shibata, K., et al. 2000. J Chromatogr B Biomed Sci Appl. 749: 281-5. PMID: 11145065
- The occurrence of nicotinic acid mononucleotide in Fusarium sp. | BALLIO, A. and RUSSI, S. 1959. Arch Biochem Biophys. 85: 567-9. PMID: 13796279
- Structure of nicotinic acid mononucleotide adenylyltransferase from Bacillus anthracis. | Lu, S., et al. 2008. Acta Crystallogr Sect F Struct Biol Cryst Commun. 64: 893-8. PMID: 18931430
- Theoretical studies of the quinolinic acid to nicotinic acid mononucleotide transformation. | Rozenberg, A. and Lee, JK. 2008. J Org Chem. 73: 9314-9. PMID: 18954112
- Pyridine metabolism in tea plants: salvage, conjugate formation and catabolism. | Ashihara, H. and Deng, WW. 2012. J Plant Res. 125: 781-91. PMID: 22527843
- Comparison of the formation of nicotinic acid conjugates in leaves of different plant species. | Ashihara, H., et al. 2012. Plant Physiol Biochem. 60: 190-5. PMID: 22983143
- [Effect of overexpression of nicotinic acid mononucleotide adenylyltransferase on succinic acid production in Escherichia coli NZN111]. | Gou, D., et al. 2012. Sheng Wu Gong Cheng Xue Bao. 28: 1059-69. PMID: 23289308
- Structural and Functional Characterization of Plasmodium falciparum Nicotinic Acid Mononucleotide Adenylyltransferase. | Bathke, J., et al. 2016. J Mol Biol. 428: 4946-4961. PMID: 27984041
- Engineering Escherichia coli Nicotinic Acid Mononucleotide Adenylyltransferase for Fully Active Amidated NAD Biosynthesis. | Wang, X., et al. 2017. Appl Environ Microbiol. 83: PMID: 28455340
- Hyperthermophilic Archaeon Thermococcus kodakarensis Utilizes a Four-Step Pathway for NAD+ Salvage through Nicotinamide Deamination. | Hachisuka, SI., et al. 2018. J Bacteriol. 200: PMID: 29555696
- Adenine Nucleotide Metabolites in Uremic Erythrocytes as Metabolic Markers of Chronic Kidney Disease in Children. | Piechowicz, J., et al. 2021. J Clin Med. 10: PMID: 34768727
- Bifunctional NadC Homologue PyrZ Catalyzes Nicotinic Acid Formation in Pyridomycin Biosynthesis. | Zhou, Z., et al. 2023. ACS Chem Biol. 18: 141-150. PMID: 36517246
- [Pyridine nucleotides. II. Isolation and identification of alpha-isomers of nicotinic acid mononucleotide and nicotinic acid-adenine dinucleotide]. | Imai, T. and Suzuki, S. 1971. Seikagaku. 43: 346-62. PMID: 4397646
- Nicotinamide mononucleotide adenylyltransferase activity in human erythrocytes. | Sestini, S., et al. 1993. Arch Biochem Biophys. 302: 206-11. PMID: 8470897
- Conversion of a cosubstrate to an inhibitor: phosphorylation mutants of nicotinic acid phosphoribosyltransferase. | Rajavel, M., et al. 1998. Biochemistry. 37: 4181-8. PMID: 9521740
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicotinic acid mononucleotide, 5 mg | sc-215565 | 5 mg | $265.00 | |||
Nicotinic acid mononucleotide, 10 mg | sc-215565A | 10 mg | $459.00 | |||
Nicotinic acid mononucleotide, 25 mg | sc-215565B | 25 mg | $836.00 | |||
Nicotinic acid mononucleotide, 100 mg | sc-215565C | 100 mg | $2499.00 |