Molecular structure of (−)-Nicotine hemisulfate salt, CAS Number: 65-30-5
(−)-Nicotine hemisulfate salt (CAS 65-30-5)
Alternate Names:
(−)-1-Methyl-2-(3-pyridyl)pyrrolidine
Application:
(−)-Nicotine hemisulfate salt is a prototype AChR (nicotinic acetylcholine receptor) agonist
CAS Number:
65-30-5
Molecular Weight:
422.54
Molecular Formula:
(C10H14N2)2•H2SO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Naturally occuring isomer containing a mixture of nicotine base and nicotine sulfate. Prototype nicotinic ACh receptor agonist.
(−)-Nicotine hemisulfate salt (CAS 65-30-5) References
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- Action of ethanol on responses to nicotine from cerebellar Purkinje neurons: relationship to methyllycaconitine (MLA) inhibition of nicotine responses. | Yang, X., et al. 1999. Neurochem Int. 35: 185-94. PMID: 10406002
- Sex differences in voluntary oral nicotine consumption by adolescent mice: a dose-response experiment. | Klein, LC., et al. 2004. Pharmacol Biochem Behav. 78: 13-25. PMID: 15159130
- Nicotine attenuates spatial learning deficits induced by sodium metavanadate. | Azami, K., et al. 2012. Neurotoxicology. 33: 44-52. PMID: 22119111
- Differences in vulnerability to nicotine-induced kindling between female and male periadolescent rats. | Gomes, PX., et al. 2013. Psychopharmacology (Berl). 225: 115-26. PMID: 22782460
- Nicotine increases lifespan and rescues olfactory and motor deficits in a Drosophila model of Parkinson's disease. | Chambers, RP., et al. 2013. Behav Brain Res. 253: 95-102. PMID: 23871228
- Electronic cigarettes induce DNA strand breaks and cell death independently of nicotine in cell lines. | Yu, V., et al. 2016. Oral Oncol. 52: 58-65. PMID: 26547127
- Developing a model of limited-access nicotine consumption in C57Bl/6J mice. | Kasten, CR., et al. 2016. Pharmacol Biochem Behav. 148: 28-37. PMID: 27242276
- Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons. | Oh, Y., et al. 2016. Cell Stem Cell. 19: 95-106. PMID: 27320040
- Opposite effects of moderate heat stress and hyperthermia on cholinergic system of soil nematodes Caenorhabditis elegans and Caenorhabditis briggsae. | Kalinnikova, TB., et al. 2016. J Therm Biol. 62: 37-49. PMID: 27839548
- Regulation of molecular clock oscillations and phagocytic activity via muscarinic Ca2+ signaling in human retinal pigment epithelial cells. | Ikarashi, R., et al. 2017. Sci Rep. 7: 44175. PMID: 28276525
- Use of derived adipose stem cells to reduce complications of cutaneous scarring in smokers. An experimental model in rats. | Martins, JMP., et al. 2019. Acta Cir Bras. 34: e201900605. PMID: 31432996
- Vagal α7nAChR signaling regulates α7nAChR+Sca1+ cells during lung injury repair. | Chen, X., et al. 2020. Stem Cell Res Ther. 11: 375. PMID: 32867826
- Ethanol and nicotine consumption and preference in transgenic mice overexpressing the bovine growth hormone gene. | Meliska, CJ., et al. 1995. Pharmacol Biochem Behav. 50: 563-70. PMID: 7617702
- Ethanol, nicotine, amphetamine, and aspartame consumption and preferences in C57BL/6 and DBA/2 mice. | Meliska, CJ., et al. 1995. Pharmacol Biochem Behav. 50: 619-26. PMID: 7617710
Activator of:
AChR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(−)-Nicotine hemisulfate salt, 25 ml | sc-263947 | 25 ml | $45.00 |