Date published: 2025-10-6

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Nickel(II) sulfate hexahydrate (CAS 10101-97-0)

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Application:
Nickel(II) sulfate hexahydrate is used in nickel plating
CAS Number:
10101-97-0
Molecular Weight:
262.85
Molecular Formula:
NiSO46H2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Nickel(II) sulfate hexahydrate is a compound that contains nickel, sulfur, and oxygen atoms. In aqueous solutions, it dissociates into nickel ions and sulfate ions, which can participate in redox reactions and coordination chemistry. The hexahydrate form of nickel(II) sulfate is the most stable and encountered in laboratory applications. It is a blue-green crystalline solid that is easily soluble in water. In biochemistry, it is used as a source of nickel ions for studying the role of this metal in biological systems. It can serve as a catalyst in certain organic reactions. Its properties make it investigating the behavior of metal ions in biological and chemical processes.


Nickel(II) sulfate hexahydrate (CAS 10101-97-0) References

  1. Enrichment of iron(III), cobalt(II), nickel(II), and copper(II) by solid-phase extraction with 1,8-dihydroxyanthraquinone anchored to silica gel before their determination by flame atomic absorption spectrometry.  |  Goswami, A. and Singh, AK. 2002. Anal Bioanal Chem. 374: 554-60. PMID: 12373409
  2. NTP Toxicology and Carcinogenesis Studies of Nickel Sulfate Hexahydrate (CAS No. 10101-97-0) in F344 Rats and B6C3F1 Mice (Inhalation Studies).  |  ,. 1996. Natl Toxicol Program Tech Rep Ser. 454: 1-380. PMID: 12587012
  3. Lack of micronuclei formation in bone marrow of rats after repeated oral exposure to nickel sulfate hexahydrate.  |  Oller, AR. and Erexson, G. 2007. Mutat Res. 626: 102-10. PMID: 17052950
  4. Oral carcinogenicity study with nickel sulfate hexahydrate in Fischer 344 rats.  |  Heim, KE., et al. 2007. Toxicol Appl Pharmacol. 224: 126-37. PMID: 17692353
  5. Mononuclear versus dinuclear complex formation in nickel(II) sulfate/phenyl(2-pyridyl)ketone oxime chemistry depending on the ligand to metal reaction ratio: synthetic, spectral and structural studies.  |  Papatriantafyllopoulou, C., et al. 2008. Spectrochim Acta A Mol Biomol Spectrosc. 70: 718-28. PMID: 17923432
  6. Development and utilization of an ex vivo bromodeoxyuridine local lymph node assay protocol for assessing potential chemical sensitizers.  |  Williams, WC., et al. 2015. J Appl Toxicol. 35: 29-40. PMID: 24532485
  7. Concentrations and stability of methyl methacrylate, glutaraldehyde, formaldehyde and nickel sulfate in commercial patch test allergen preparations.  |  Siegel, PD., et al. 2014. Contact Dermatitis. 70: 309-15. PMID: 24731086
  8. Associated positive patch test reactions to standard contact allergens: 10-year data from the Slovenian E-Surveillance System.  |  Dugonik, A., et al. 2021. Contact Dermatitis. 85: 17-25. PMID: 33368304
  9. Patch test-relevant concentrations of metal salts cause localized cytotoxicity, including apoptosis, in skin ex vivo.  |  Zhang, Y., et al. 2021. Contact Dermatitis. 85: 531-542. PMID: 34268774
  10. Comparative carcinogenic effects of nickel subsulfide, nickel oxide, or nickel sulfate hexahydrate chronic exposures in the lung.  |  Dunnick, JK., et al. 1995. Cancer Res. 55: 5251-6. PMID: 7585584

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Nickel(II) sulfate hexahydrate, 100 g

sc-212369
100 g
$55.00

Nickel(II) sulfate hexahydrate, 500 g

sc-212369A
500 g
$200.00