Nicardipine-d3 Hydrochloride (CAS 1432061-50-1)
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Nicardipine-d3 is a chemical compound that may function as a calcium channel blocker. It may inhibit the influx of calcium ions into cardiac and smooth muscle, leading to relaxation and dilation of blood vessels. At the molecular level, Nicardipine-d3 may target L-type calcium channels, blocking the entry of calcium ions into the cells. This action results in decreased contractility of the heart and reduced vascular tone. By interfering with the calcium signaling pathway, Nicardipine-d3 effectively modulates the excitation-contraction coupling in cardiac and smooth muscle cells. Nicardipine-D3′s mechanism of action involves binding to specific sites on the calcium channels, thereby preventing the conformational changes necessary for calcium ion entry. In experimental applications, Nicardipine-d3 may be utilized to investigate the role of calcium channels in cardiovascular physiology and to study the effects of calcium channel blockade on cardiac and vascular function.
Nicardipine-d3 Hydrochloride (CAS 1432061-50-1) References
- Development of an Oral Liquid Formulation of Nicardipine Hydrochloride Compounded with Simple Excipients for the Treatment of Pediatric Hypertension. | Cavelier, M., et al. 2023. Pharmaceutics. 15: PMID: 36839767
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nicardipine-d3 Hydrochloride, 1 mg | sc-219353 | 1 mg | $359.00 |