NG,NG-Dimethylarginine-d6 Dihydrochloride (CAS 1313730-20-9)
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ADMA-d6 (NG,NG-dimethylarginine-d6 Dihydrochloride) serves as an internal standard in the precise quantification of NG,NG-dimethyl-L-arginine through GC- or LC-MS techniques. ADMA, an endogenous inhibitor of nitric oxide synthase (NOS), is synthesized from arginine by protein arginine methyltransferases (PRMTs) and metabolized by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). Elevated ADMA levels have been observed alongside increased blood pressure in Dahl salt-sensitive rats following a high-salt diet. The utilization of NG,NG-dimethylarginine-d6 Dihydrochloride as an internal standard aids in accurate determination of NG,NG-dimethyl-L-arginine concentrations, enabling precise analysis using GC- or LC-MS methodologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NG,NG-Dimethylarginine-d6 Dihydrochloride, 2.5 mg | sc-497758 | 2.5 mg | $326.00 | |||
NG,NG-Dimethylarginine-d6 Dihydrochloride, 25 mg | sc-497758A | 25 mg | $2244.00 |