NFκB Inhibitor (CAS 213546-53-3)
See product citations (69)
Alternate Names:
NF-κB SN50 cell permeable inhibitory peptide; AAVALLPAVLLALLAPVQRKRQKLMP
Application:
NFκB Inhibitor is inhibits translocation of the NFκB active complex into the nucleus
CAS Number:
213546-53-3
Purity:
≥97%
Molecular Weight:
2781.50
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
NFkappaB Inhibitor is a synthetic inhibitor for NFkappaB. This inhibitor contains Noxious Liquid Substance (NLS) residues 360-369 of NFkappaB p50. This inhibits translocation of the NFkappaB active complex into the nucleus.
NFκB Inhibitor (CAS 213546-53-3) References
- An intracellular targeted NLS peptide inhibitor of karyopherin alpha:NF-kappa B interactions. | Cunningham, MD., et al. 2003. Biochem Biophys Res Commun. 300: 403-7. PMID: 12504098
- Characterization of the role of full-length CRMP3 and its calpain-cleaved product in inhibiting microtubule polymerization and neurite outgrowth. | Aylsworth, A., et al. 2009. Exp Cell Res. 315: 2856-68. PMID: 19559021
- Rabies virus glycoprotein-amplified hierarchical targeted hybrids capable of magneto-electric penetration delivery to orthotopic brain tumor. | Su, YL., et al. 2020. J Control Release. 321: 159-173. PMID: 32045622
- Hypertonic saline mediates the NLRP3/IL-1β signaling axis in microglia to alleviate ischemic blood-brain barrier permeability by downregulating astrocyte-derived VEGF in rats. | Wang, QS., et al. 2020. CNS Neurosci Ther. 26: 1045-1057. PMID: 32529750
- Astrocyte-derived VEGF increases cerebral microvascular permeability under high salt conditions. | Deng, Z., et al. 2020. Aging (Albany NY). 12: 11781-11793. PMID: 32568100
- TNF-a Is a Potent Stimulator of Tc9-Cell Differentiation. | Yang, S., et al. 2020. J Immunother. 43: 265-272. PMID: 32842039
- Cyclin D1 mediated by the nuclear translocation of nuclear factor kappa B exerts an oncogenic role in lung cancer. | Wang, X., et al. 2022. Bioengineered. 13: 6866-6879. PMID: 35246017
- Preparation of functionally active cell-permeable peptides by single-step ligation of two peptide modules. | Zhang, L., et al. 1998. Proc Natl Acad Sci U S A. 95: 9184-9. PMID: 9689055
- Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50. | Torgerson, TR., et al. 1998. J Immunol. 161: 6084-92. PMID: 9834092
- NADPH Oxidase Contributes to Oxidative Stress and Reduced eNOS Phosphorylation during Hyperinsulinemia in Human Skeletal Muscle Arterioles and Microvascular Endothelial Cells | Mahmoud, A. M., Ali, M. M., Miranda, E., Mey, J., Blackburn, B., Robinson, A.,.. & Phillips, S. A. 2016. The FASEB Journal. 30: 1276-2.
Inhibitor of:
CT120, IFN-α16, Klotho, LOC728697, MGC33894, and NF kappa B.Activator of:
CYB5D2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NFκB Inhibitor, 0.5 mg | sc-3060 | 0.5 mg | $169.00 | |||
NFκB Inhibitor, 5 mg | sc-3060A | 5 mg | $743.00 | |||
NFκB Inhibitor, 10 mg | sc-3060B | 10 mg | $1294.00 |