Molecular structure of NF-kB Activation Inhibitor IV, CAS Number: 139141-12-1
NF-kB Activation Inhibitor IV (CAS 139141-12-1)
Alternate Names:
(E)-2-Fluoro-4′-methoxystilbene
Application:
NF-kB Activation Inhibitor IV is a cell-permeable inhibitor of NF kappa B Activation
CAS Number:
139141-12-1
Purity:
≥98%
Molecular Weight:
228.1
Molecular Formula:
C15H13FO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
NF-kB Activation Inhibitor IV is a cell-permeable trans-stilbene Resveratrol analog that exhibits enhanced anti-inflammatory potency, but no anti-oxidant activity.
NF-kB Activation Inhibitor IV (CAS 139141-12-1) References
- Substituted trans-stilbenes, including analogues of the natural product resveratrol, inhibit the human tumor necrosis factor alpha-induced activation of transcription factor nuclear factor kappaB. | Heynekamp, JJ., et al. 2006. J Med Chem. 49: 7182-9. PMID: 17125270
- The nuclear factor κB inhibitor (E)-2-fluoro-4'-methoxystilbene inhibits firefly luciferase. | Braeuning, A. and Vetter, S. 2012. Biosci Rep. 32: 531-7. PMID: 22789175
- [Inhibition of NF-kB Activation Decreases Resistance in Acute Myeloid Leukemia Cells to TRAIL-induced Apoptosis in Multicellular Aggregates]. | Fadeev, RS., et al. 2015. Biofizika. 60: 1146-50. PMID: 26841509
- Tumor necrosis factor-α regulates angiogenesis of BeWo cells via synergy of PlGF/VEGFR1 and VEGF-A/VEGFR2 axes. | Tanaka, K., et al. 2018. Placenta. 74: 20-27. PMID: 30591201
- IL-17A induction of ADAMTS-5 in differentiated THP-1 cells is modulated by the ERK signaling pathway. | Thou, EMH., et al. 2020. Eur Cytokine Netw. 31: 59-67. PMID: 32933893
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NF-kB Activation Inhibitor IV, 10 mg | sc-222063 | 10 mg | $122.00 |