Molecular structure of NF 023, CAS Number: 104869-31-0
NF 023 (CAS 104869-31-0)
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Alternate Names:
8,8′-[Carbonylbis(imino-3,1-phenylene)]bis-(1,3,5-naphthalenetrisulfonic Acid), 6Na
Application:
NF 023 is a subtype selective, competitive and reversible P2X1 receptor antagonist
CAS Number:
104869-31-0
Purity:
≥98%
Molecular Weight:
1162.88
Molecular Formula:
C35H20N4O21S6•6Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
NF 023 is a subtype selective, competitive and reversible P2X1 receptor antagonist. Displays IC50 values of 0.21, 28.9, > 50 and > 100 μM for human P2X1, P2X3, P2X2, and P2X4-mediated responses respectively. Selective over adrenoceptors, histamine and P2Y receptors. Also, NF 023 selectively inhibits the α-subunit of Go/i (EC50 ~ 300 nM).
Inhibitor of:
ART2, EG436049, FAPP2, Gα 15, Gα i-1, Gα i-3, Gα s, Gα t2, Gγ 10, GAIP, GNGT2, GPB5, GPR family (GPCR;G protein-coupled), GPR101, GPR115, GPR128, GPR139, GPR144, GPR178, Olfr612, OR1A2, OR4C3, OR5B3, OR5M3, OR6B1, P2X1, P2X2, P2X6, Regulator of G protein signaling (RGS), RGS1, RGS14, RGS21, RGS22, RIC-8A, urotensin II, and Vmn2r96.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NF 023, 10 mg | sc-204124 | 10 mg | $158.00 | |||
NF 023, 50 mg | sc-204124A | 50 mg | $617.00 |