Neuromedin N (CAS 102577-25-3)
QUICK LINKS
Neuromedin N is a neuropeptide that functions as a neurotransmitter in the central nervous system. It acts as a ligand for the neuromedin U receptor, binding to and activating this receptor to initiate intracellular signaling cascades. This activation leads to the modulation of neuronal activity and neurotransmitter release, ultimately influencing various physiological processes. Neuromedin N plays a role in the regulation of feeding behavior, energy homeostasis, and stress responses. At the molecular level, it interacts with specific receptors and signaling pathways to exert its effects on neuronal function and neurotransmission. Its mode of action involves the activation of downstream signaling molecules and the modulation of neuronal excitability, contributing to the regulation of various physiological functions within the central nervous system.
Neuromedin N (CAS 102577-25-3) References
- Modulation by neurotensin and neuromedin N of adherence and chemotaxis capacity of murine lymphocytes. | Garrido, JJ., et al. 1992. Regul Pept. 41: 27-37. PMID: 1333624
- Neuromedin-N inhibits migrating myoelectric complex and induces irregular spiking in the small intestine of rats; comparison with neurotensin. | Schultz, I., et al. 1991. Regul Pept. 35: 197-205. PMID: 1758975
- Ligand-mediated dephosphorylation signaling for MAP kinase. | Shults, NV., et al. 2018. Cell Signal. 52: 147-154. PMID: 30213686
- Pro-Neurotensin/Neuromedin N and Risk of Cognitive Impairment in a Prospective Study. | Nicoli, CD., et al. 2020. J Alzheimers Dis. 76: 1403-1412. PMID: 32623400
- Preclinical Evaluation of NHS-Activated Gold Nanoparticles Functionalized with Bombesin or Neurotensin-Like Peptides for Targeting Colon and Prostate Tumours. | Chilug, LE., et al. 2020. Molecules. 25: PMID: 32722221
- Pro-neurotensin/neuromedin N and risk of ischemic stroke: The REasons for Geographic And Racial Differences in Stroke (REGARDS) study. | Nicoli, CD., et al. 2020. Vasc Med. 25: 534-540. PMID: 33089749
- Pro-Neurotensin/Neuromedin N and Risk of Incident Metabolic Syndrome and Diabetes Mellitus in the REGARDS Cohort. | Nicoli, CD., et al. 2021. J Clin Endocrinol Metab. 106: e3483-e3494. PMID: 34013344
- Pro-neurotensin/Neuromedin N and Hypertension Risk: A Prospective Study. | Nicoli, CD., et al. 2022. Am J Hypertens. 35: 281-288. PMID: 34655288
- Potential novel biomarkers in small intestine for obesity/obesity resistance revealed by multi-omics analysis. | Pang, Y., et al. 2022. Lipids Health Dis. 21: 98. PMID: 36209126
- Multi-omics analysis reveals underlying host responses in pediatric respiratory syncytial virus pneumonia. | Huang, X., et al. 2023. iScience. 26: 106329. PMID: 36968072
- Association of NAD+ levels with metabolic disease in a community-based study. | Liu, Y., et al. 2023. Front Endocrinol (Lausanne). 14: 1164788. PMID: 37152934
- Investigations on the acute effects of neuropeptides on the pituitary-adrenocortical function in normal and cold-stressed rats. II. Neurotensin and neuromedin N. | Malendowicz, LK., et al. 1995. Exp Toxicol Pathol. 47: 41-5. PMID: 7719120
- Stimulation of phagocytic function in mouse macrophages by neurotensin and neuromedin N. | De la Fuente, M., et al. 1993. J Neuroimmunol. 42: 97-104. PMID: 8380808
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Neuromedin N, 1 mg | sc-396103 | 1 mg | $84.00 | |||
Neuromedin N, 2 mg | sc-396103A | 2 mg | $111.00 | |||
Neuromedin N, 5 mg | sc-396103B | 5 mg | $196.00 |