Date published: 2025-12-13

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Neurokinin-1 Receptor Antagonist (CAS 337505-63-2)

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Alternate Names:
N-(3-chlorophenyl)-2-(4-phenyl-5-(4-pyridyl)(1,2,4-triazol-3-ylthio))acetamide
Application:
Neurokinin-1 Receptor Antagonist is a high-affinity antagonist for NK1
CAS Number:
337505-63-2
Molecular Weight:
421.9
Molecular Formula:
C21H16ClN5OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Neurokinin-1 Receptor Antagonist is a triazolyl-amide compound that acts as a high-affinity (Ki = 251 nM) antagonist for NK1, the substance P-specific neurokinin receptor. Shown to compete with substance P binding to NK1 on whole CHO cells. Exhibits similar pharmacophore features as, but is structurally distinct from, CP-96345.


Neurokinin-1 Receptor Antagonist (CAS 337505-63-2) References

Evers, A., and Klebe, G. 2004. Angew. Chem. Int. Ed. 43, 248.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Neurokinin-1 Receptor Antagonist, 1 mg

sc-222057
1 mg
$133.00