Neu5Ac α(2-3)Gal β(1-4)GlcNAc-β-pNP (CAS 501427-92-5)

Neu5Ac α(2-3)Gal β(1-4)GlcNAc-β-pNP, a synthetic glycoside compound, has emerged as a pivotal tool in glycobiology research, particularly in elucidating glycan-mediated interactions and cellular signaling pathways. Its structural mimicry of natural glycan epitopes enables precise probing of glycan-binding proteins and their roles in various biological processes. Researchers have utilized Neu5Ac α(2-3)Gal β(1-4)GlcNAc-β-pNP to investigate glycan-dependent cellular recognition events, such as cell adhesion, migration, and immune response modulation. Moreover, its enzymatic susceptibility allows for the development of glycosidase assays for the detection and characterization of glycan-processing enzymes. By employing Neu5Ac α(2-3)Gal β(1-4)GlcNAc-β-pNP as a substrate, researchers can study the kinetics and specificities of glycosidases involved in glycan metabolism and remodeling. Furthermore, this compound serves as a valuable tool in the development of glycan-based biosensors and diagnostic assays, exploiting its ability to interact with glycan-binding proteins with high specificity and affinity. The elucidation of Neu5Ac α(2-3)Gal β(1-4)GlcNAc-β-pNP′s mechanisms of action continues to drive research endeavors aimed at unraveling the complex roles of glycans in cellular physiology and disease pathogenesis, paving the way for the development of novel research methodologies and diagnostic tools in glycobiology.