Date published: 2025-9-25

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Nervonic acid (CAS 506-37-6)

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Alternate Names:
cis-15-Tetracosenoic acid
CAS Number:
506-37-6
Molecular Weight:
366.62
Molecular Formula:
C24H46O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Nervonic acid, a monounsaturated fatty acid primarily found in the brain and nervous system, has gained attention in scientific research for its potential implications in neurological disorders and lipid metabolism. Recent studies have explaind its role as a modulator of membrane fluidity and neuronal function, suggesting its involvement in synaptic transmission and plasticity mechanisms. Moreover, nervonic acid has been investigated for its neuroprotective properties, with research indicating its ability to mitigate oxidative stress and inflammation in neuronal cells. Additionally, its involvement in myelin synthesis has been of particular interest in studies focused on demyelinating diseases such as multiple sclerosis, where deficiencies in nervonic acid metabolism have been observed. Furthermore, emerging research suggests potential applications of nervonic acid in cognitive enhancement and mood regulation, though further studies are warranted to explain its precise mechanisms of action in these contexts. Beyond its neurological implications, nervonic acid′s role in lipid metabolism has also been explored, with investigations highlighting its potential as a biomarker for metabolic disorders and as a target for interventions aimed at modulating lipid homeostasis. Overall, nervonic acid stands as a promising molecule in neuroscience and lipid biology research, offering insights into fundamental processes underlying brain function and neurodegenerative diseases.


Nervonic acid (CAS 506-37-6) References

  1. Biosynthesis of nervonic acid and perspectives for its production by microalgae and other microorganisms.  |  Fan, Y., et al. 2018. Appl Microbiol Biotechnol. 102: 3027-3035. PMID: 29478140
  2. A mini review of nervonic acid: Source, production, and biological functions.  |  Li, Q., et al. 2019. Food Chem. 301: 125286. PMID: 31382110
  3. Nervonic acid limits weight gain in a mouse model of diet-induced obesity.  |  Keppley, LJW., et al. 2020. FASEB J. 34: 15314-15326. PMID: 32959931
  4. A Review of Nervonic Acid Production in Plants: Prospects for the Genetic Engineering of High Nervonic Acid Cultivars Plants.  |  Liu, F., et al. 2021. Front Plant Sci. 12: 626625. PMID: 33747006
  5. Perspectives of nervonic acid production by Yarrowia lipolytica.  |  Giwa, AS. and Ali, N. 2022. Biotechnol Lett. 44: 193-202. PMID: 35119573
  6. Nervonic Acid Attenuates Accumulation of Very Long-Chain Fatty Acids and is a Potential Therapy for Adrenoleukodystrophy.  |  Terluk, MR., et al. 2022. Neurotherapeutics. 19: 1007-1017. PMID: 35378685
  7. The Advancements and Prospects of Nervonic Acid Production.  |  Liu, F., et al. 2022. J Agric Food Chem. 70: 12772-12783. PMID: 36166330
  8. Improved colonic inflammation by nervonic acid via inhibition of NF-κB signaling pathway of DSS-induced colitis mice.  |  Yuan, SN., et al. 2023. Phytomedicine. 112: 154702. PMID: 36764096
  9. Nervonic acid improves liver inflammation in a mouse model of Parkinson's disease by inhibiting proinflammatory signaling pathways and regulating metabolic pathways.  |  Wang, X., et al. 2023. Phytomedicine. 117: 154911. PMID: 37276724
  10. Research Progress of Nervonic Acid Biosynthesis.  |  Ling, C., et al. 2023. J Oleo Sci. 72: 889-900. PMID: 37704446

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Nervonic acid, 100 mg

sc-215555
100 mg
$76.00

Nervonic acid, 250 mg

sc-215555A
250 mg
$152.00

Nervonic acid, 500 mg

sc-215555B
500 mg
$300.00